POTENTIAL OF THE ESSENTIAL OIL OF ALPINIA ZERUMBET (PERS.) B.L. BURTT & R. M. SM. (COLONIA) AGAINST ALZHEIMER'S DISEASE, THROUGH ANTIOXIDANT AND ANTICHOLINESTERASE ACTIVITY IN VITRO AND IN SILICO STUDIES

Autores/as

  • Selene M. de Morais Autor/a
  • Felipe W. V. Paulino Autor/a
  • Daniel P. de Oliveira Autor/a
  • Rita de C. A. Pereira Autor/a
  • Wildson Max B. da Silva Autor/a
  • Daniela R. Alves Autor/a
  • Jacilene Silva Autor/a
  • Emmanuel S. Marinho Autor/a

DOI:

https://doi.org/10.56238/arev7n1-153

Palabras clave:

Cholinergic Hypothesis, Free Radicals, Molecular Docking

Resumen

The plant Alpinia zerumbet, commonly known as "Colônia," is widely utilized in traditional medicine for addressing anxiety and hypertension, both of which are associated with oxidative damage in the brain. This study aimed to explore the antioxidant and anticholinesterase properties of the essential oil extracted from its leaves. Additionally, an in-silico investigation was carried out on several essential oil constituents concerning the acetylcholinesterase enzyme. The GC/MS analysis identified nineteen volatile compounds, mainly monoterpenoids (98.41%), particularly terpinen-4-ol, eucalyptol,

Descargas

Los datos de descarga aún no están disponibles.

Descargas

Publicado

2025-01-20

Número

Vol. 7 Núm. 1 (2025)

Sección

Articles

Cómo citar

DE MORAIS, Selene M.; PAULINO, Felipe W. V.; DE OLIVEIRA, Daniel P.; PEREIRA, Rita de C. A.; DA SILVA, Wildson Max B.; ALVES, Daniela R.; SILVA, Jacilene; MARINHO, Emmanuel S. POTENTIAL OF THE ESSENTIAL OIL OF ALPINIA ZERUMBET (PERS.) B.L. BURTT & R. M. SM. (COLONIA) AGAINST ALZHEIMER’S DISEASE, THROUGH ANTIOXIDANT AND ANTICHOLINESTERASE ACTIVITY IN VITRO AND IN SILICO STUDIES. ARACÊ , [S. l.], v. 7, n. 1, p. 2516–2534, 2025. DOI: 10.56238/arev7n1-153. Disponível em: https://periodicos.newsciencepubl.com/arace/article/view/2890. Acesso em: 5 feb. 2025.