DENGUE VIRUS INFECTION LEADING TO ACUTE ACALCULOUS CHOLECYSTITIS
DOI:
https://doi.org/10.56238/arev7n9-296Keywords:
Acalculous Cholecystitis, Dengue, Severe Dengue, ShockAbstract
Brazil is one of the countries most affected by dengue, accounting for approximately 23 million cases worldwide between 1980 and 2017. Dengue virus (DENV) infection can present with headache, fever, myalgia, arthralgia, and skin rash, but it can also present atypically, with gastrointestinal manifestations, such as acute acalculous cholecystitis (AAC). This condition is characterized by inflammation of the gallbladder in the absence of gallstones and may or may not be associated with infection. The incidence rates of AAC have ranged from 6% to 52%, a difference attributed to the use of different diagnostic criteria. Several hypotheses have been proposed to explain its pathophysiology, including the possibility of direct viral invasion associated with biliary stasis, endotoxemia, and, in some cases, secondary bacterial translocation. Furthermore, a correlation has been observed between gallbladder thickening, the severity of the infection, and the risk of hypovolemic shock, a potentially fatal condition. Therefore, this article sought to enrich knowledge about AAC in order to prevent serious or even fatal complications.
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References
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