SELF-MEDICATION WITH GLP-1 ANALOGS: CLINICAL RISKS AND THE PHARMACIST’S ROLE IN RATIONAL USE

Authors

  • Ruth Maria da Silva Santos Author
  • Luana Vitória Alves Amorim Author
  • Lívia Maria Santos de Lima Author
  • Jéssica Maria Pereira Author
  • João Vitor Araujo do Nascimento Silva Author
  • Rilley Julianne Albuquerque Felismino Author
  • Cecília Gomes Figueiredo Author
  • Maria Aline Barros Fidelis de Moura Author

DOI:

https://doi.org/10.56238/arev8n4-040

Keywords:

GLP-1 Analogs, Self-Medication, Irrational Use, Patient Safety, Pharmaceutical Care

Abstract

 Given the increasing use of GLP-1 analogs for cosmetic purposes and outside of clinical indications, it is important to understand the risks associated with self-medication and the inappropriate use of these drugs, as such practices can harm patients. The objective of this study was to assess the main risks associated with the use of these medications, as well as to analyze the role of pharmacists in promoting their safe and rational use. To this end, an integrative literature review was conducted in databases using pre-defined selection criteria. A total of 22 scientific articles were analyzed, and the results showed that gastrointestinal effects are the most frequently reported among users, in addition to the occurrence of more serious adverse events, such as ketoacidosis, pancreatitis, and neurological disorders. It was also found that pharmacist supervision is essential, as it helps guide patients, promotes safe use, and helps reduce inappropriate practices. Finally, although this class of medications offers benefits in the treatment of obesity, their use without proper supervision can pose significant risks, underscoring the need for further studies and professional monitoring to ensure long-term safety.   

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References

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Published

2026-04-17

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Articles

How to Cite

SANTOS, Ruth Maria da Silva; AMORIM, Luana Vitória Alves; DE LIMA, Lívia Maria Santos; PEREIRA, Jéssica Maria; SILVA, João Vitor Araujo do Nascimento; FELISMINO, Rilley Julianne Albuquerque; FIGUEIREDO, Cecília Gomes; DE MOURA, Maria Aline Barros Fidelis. SELF-MEDICATION WITH GLP-1 ANALOGS: CLINICAL RISKS AND THE PHARMACIST’S ROLE IN RATIONAL USE. ARACÊ , [S. l.], v. 8, n. 4, p. e12888, 2026. DOI: 10.56238/arev8n4-040. Disponível em: https://periodicos.newsciencepubl.com/arace/article/view/12888. Acesso em: 18 apr. 2026.