DIFFICULT AIRWAY IN CRITICAL SCENARIOS: A SYSTEMATIC REVIEW ON ASSESSMENT, TECHNOLOGIES, AND PATIENT SAFETY

Authors

  • Eduardo Vilela Rodrigues Author
  • José Matos de Oliveira Neto Author
  • Julia Yurie Nakao Ravazzi Author
  • Laura Favero Janini Abboud Author
  • Maria Eduarda Colmanetti Rezende Author
  • Ana Laura Fugita Santos Author
  • Amanda Freire Candido Author

DOI:

https://doi.org/10.56238/levv16n55-030

Keywords:

Airway Management, Critical Patients, Orotracheal Intubation, Definitive Airway

Abstract

Objective: This systematic review aims to investigate the main strategies for the assessment and safe management of difficult airways in critically ill patients. Methodology: The research question was constructed using the PVO (Population, Variable, Objective) strategy. The literature search was performed in the PubMed, Embase, and Science Direct databases using the following English descriptors: (“difficult airway” OR “difficult intubation” OR “airway management”) AND (“critical care” OR “emergency department” OR “intensive care unit”) AND (“airway assessment” OR “predictive tests” OR ultrasound) AND (‘videolaryngoscopy’ OR “fiberoptic intubation”) AND (“patient safety” OR complications). Initially, 333 articles were identified. After applying the eligibility criteria, 12 studies were selected. Results: The identification and management of difficult airways in critically ill patients require integrated approaches that increase initial intubation success and reduce adverse events. Ultrasound has emerged as a useful complementary method, allowing assessment of subglottic anatomy, prediction of difficulties, and rapid confirmation of tube placement; studies show high agreement with radiography, especially using the tracheal rings method. During the intubation phase, videolaryngoscopy has demonstrated superiority over direct laryngoscopy, significantly reducing the need for multiple attempts. The use of bougie as an initial strategy (“bougie-first”), especially in combination with videolaryngoscopy, increased first-attempt success even during continuous chest compressions. Preoxygenation strategies also contribute to greater safety: high-flow nasal cannula (HFNC) proved superior to bag-valve mask in reducing desaturations and adverse events, maintaining continuous oxygenation during laryngoscopy. Conclusion: Taken together, the evidence indicates that the combination of video laryngoscopy, bougie-first, preoxygenation with HFNC, and ultrasound for assessment and confirmation represents the most effective set of contemporary strategies for recognizing and managing the difficult airway in critically ill patients.

Downloads

Download data is not yet available.

References

ADMASS, B. A. et al. Evidence-based airway management protocol for a critical ill patient in medical intensive care unit: systematic review. Annals of Medicine and Surgery (London), v. 80, 2022. DOI: 10.1016/j.amsu.2022.104284. DOI: https://doi.org/10.1016/j.amsu.2022.104284

AHMED, A.; AZIM, A. Difficult tracheal intubation in critically ill. Journal of Intensive Care, v. 6, p. 49, 2018. DOI: 10.1186/s40560-018-0318-4. DOI: https://doi.org/10.1186/s40560-018-0318-4

ARAÚJO, B. et al. Video versus direct laryngoscopy in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials. Critical Care, v. 28, p. 1, 2024. DOI: 10.1186/s13054-023-04727-9. DOI: https://doi.org/10.1186/s13054-023-04727-9

CABRINI, L.; PALLANCH, O.; PIERI, M.; ZANGRILLO, A. Preoxygenation for tracheal intubation in critically ill patients: one technique does not fit all. Journal of Thoracic Disease, v. 11, supl. 9, p. S1299–S1303, 2019. DOI: 10.21037/jtd.2019.04.67 DOI: https://doi.org/10.21037/jtd.2019.04.67

DATTA, S. et al. Diagnostic accuracy of airway ultrasound in confirming the endotracheal tube depth in critically ill children. American Journal of Emergency Medicine, v. 85, p. 52-58, nov. 2024. DOI: 10.1016/j.ajem.2024.08.012. DOI: https://doi.org/10.1016/j.ajem.2024.08.012

GIBBS, K. W. et al. Noninvasive Ventilation for Preoxygenation During Emergency Intubation. The New England Journal of Medicine, 2024. DOI: 10.1056/NEJMoa2313680. DOI: https://doi.org/10.1056/NEJMoa2313680

GOTTLIEB, M.; O’BRIEN, J. R.; FERRIGNO, N.; SUNDARAM, T. Point-of-care ultrasound for airway management in the emergency and critical care setting. Clinical and Experimental Emergency Medicine, v. 11, n. 1, p. 22–32, 2024. DOI: 10.15441/ceem.23.094. DOI: https://doi.org/10.15441/ceem.23.094

GUITTON, C. et al. Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomized clinical trial. Intensive Care Medicine, v. 45, n. 4, p. 447–458, 2019. DOI: 10.1007/s00134-019-05529-w. DOI: https://doi.org/10.1007/s00134-019-05529-w

JANZ, D. R. et al. Randomized trial of video laryngoscopy for endotracheal intubation of critically ill adults. Critical Care Medicine, v. 44, n. 11, p. 1980–1987, 2016. DOI: 10.1097/CCM.0000000000001841. DOI: https://doi.org/10.1097/CCM.0000000000001841

JIANG, J. et al. Video laryngoscopy does not improve the intubation outcomes in emergency and critical patients: a systematic review and meta-analysis of randomized controlled trials. Critical Care, v. 21, p. 288, 2017. DOI: 10.1186/s13054-017-1885-9. DOI: https://doi.org/10.1186/s13054-017-1885-9

JOSHI, Raj et al. Difficult airway characteristics associated with first-attempt failure at intubation using video laryngoscopy in the intensive care unit. Annals of the American Thoracic Society, v. 14, n. 3, p. 368–375, 2017. DOI: 10.1513/AnnalsATS.201606-472OC. DOI: https://doi.org/10.1513/AnnalsATS.201606-472OC

KWON, Y. S. et al. Incidence and outcomes of cricothyrotomy in the “cannot intubate, cannot oxygenate” situation. Medicine, v. 98, n. 42, e17713, 2019. DOI: 10.1097/MD.0000000000017713. DOI: https://doi.org/10.1097/MD.0000000000017713

LASCARROU, J. B. et al. Video laryngoscopy vs direct laryngoscopy on successful first-pass orotracheal intubation among ICU patients: a randomized clinical trial. JAMA, v. 317, n. 5, p. 483–493, 2017. DOI: 10.1001/jama.2016.20603. DOI: https://doi.org/10.1001/jama.2016.20603

MOSIER, J. M. et al. Video laryngoscopy improves intubation success and reduces esophageal intubations compared to direct laryngoscopy in the medical intensive care unit. Critical Care, v. 17, n. 5, p. R237, 2013. DOI: https://doi.org/10.1186/cc13061

PREKKER, M. E. et al. Video versus direct laryngoscopy for tracheal intubation of critically ill adults. New England Journal of Medicine, v. 389, n. 5, p. 418–429, 2023. DOI: 10.1056/NEJMoa2301601. DOI: https://doi.org/10.1056/NEJMoa2301601

RUETZLER, K.; BUSTAMANTE, S.; SCHMIDT, M. T. Video laryngoscopy vs direct laryngoscopy for endotracheal intubation in the operating room: a cluster randomized clinical trial. JAMA, v. 331, n. 15, p. 1279-1286, 2024. DOI: 10.1001/jama.2024.0762. DOI: https://doi.org/10.1001/jama.2024.0762

SATHIYABAMA, S. Cricothyrotomy – in unanticipated difficult intubation cases with respiratory compromise. International Archives of Otorhinolaryngology, v. 28, n. 2, p. e307–e313, 2024. DOI: https://doi.org/10.1055/s-0043-1776726

SEMLER, M. W. et al. Randomized Trial of Apneic Oxygenation During Endotracheal Intubation of the Critically Ill. American Journal of Respiratory and Critical Care Medicine, v. 193, n. 3, p. 273–280, 2016. DOI: 10.1164/rccm.201507-1294OC. DOI: https://doi.org/10.1164/rccm.201507-1294OC

XU, X. et al. Efficacy of bougie first approach for endotracheal intubation with video laryngoscopy during continuous chest compression: a randomized crossover manikin trial. BMC Anesthesiology, v. 24, n. 181, 2024. DOI: 10.1186/s12871-024-02560-3. DOI: https://doi.org/10.1186/s12871-024-02560-3

Published

2025-12-05

How to Cite

RODRIGUES, Eduardo Vilela; DE OLIVEIRA NETO, José Matos; RAVAZZI, Julia Yurie Nakao; ABBOUD, Laura Favero Janini; REZENDE, Maria Eduarda Colmanetti; SANTOS, Ana Laura Fugita; CANDIDO, Amanda Freire. DIFFICULT AIRWAY IN CRITICAL SCENARIOS: A SYSTEMATIC REVIEW ON ASSESSMENT, TECHNOLOGIES, AND PATIENT SAFETY. LUMEN ET VIRTUS, [S. l.], v. 16, n. 55, p. e10788, 2025. DOI: 10.56238/levv16n55-030. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/10788. Acesso em: 8 dec. 2025.