ASOCIACIÓN ENTRE EL ÍNDICE INFLAMATORIO DE LA DIETA Y LAS CONCENTRACIONES PLASMÁTICAS DE CITOCINAS EN CORREDORES RECREACIONALES DE CALLE E INDIVIDUOS SEDENTARIOS
DOI:
https://doi.org/10.56238/arev8n3-168Palabras clave:
Dieta, Citocinas, Inflamación, Carrera, Composición CorporalResumen
Objetivo: Evaluar la asociación entre el Índice Inflamatorio de la Dieta (IID) y las concentraciones plasmáticas de citocinas en corredores recreacionales de calle e individuos sedentarios.
Métodos: Se realizó un estudio transversal con adultos corredores recreacionales y sedentarios. Se evaluaron el IID, variables de composición corporal y entrenamiento, y las concentraciones plasmáticas de citocinas inflamatorias.
Resultados: Entre los corredores, el IID mostró asociación positiva con IL-6 e IL-1β, incluso después del ajuste por edad, sexo y porcentaje de grasa corporal. En los modelos ajustados, el IID mantuvo asociación con IL-6 (β = 28,4%; IC95%: 8,5–51,2; p = 0,006) e IL-1β (β = 25,6%; IC95%: 3,1–47,0; p = 0,021). Entre los sedentarios, las correlaciones observadas entre el IID e IL-10, IL-1ra y TNF-α no permanecieron significativas después de los ajustes. Los corredores presentaron mayores concentraciones de IL-6 e IL-1β, mientras que los sedentarios mostraron mayor porcentaje de grasa corporal y asociación positiva entre el IID y la adiposidad.
Conclusión: El potencial inflamatorio de la dieta se asoció con el perfil plasmático de citocinas en corredores recreacionales, pero no en individuos sedentarios tras los ajustes. Los hallazgos sugieren perfiles inflamatorios distintos entre los grupos e indican que la calidad de la dieta puede estar relacionada con el perfil inflamatorio basal en individuos físicamente activos.
Descargas
Referencias
Akbari-Fakhrabadi, M., et al. (2024). Diet and exercise-induced inflammation. Frontiers in Nutrition, 11, 1438832. DOI: https://doi.org/10.3389/fnut.2024.1438832
Almeida-Neto, P. F. D., et al. (2025). The effect of repeated sprints on immunological modulation. Frontiers in Sports and Active Living, 7, 1662761. DOI: https://doi.org/10.3389/fspor.2025.1662761
Alves, M. D. J., et al. (2022). Changes in cytokines concentration following long-distance running. Frontiers in Physiology, 13, 838069. DOI: https://doi.org/10.3389/fphys.2022.838069
Badenhorst, C. E., et al. (2016). High carbohydrate ingestion does not attenuate post-exercise IL-6. European Journal of Applied Physiology, 116(9), 1715–1724. DOI: https://doi.org/10.1007/s00421-016-3426-7
Barros, E. S., et al. (2017). Acute and chronic effects of endurance running on inflammatory markers. Frontiers in Physiology, 8, 779. DOI: https://doi.org/10.3389/fphys.2017.00779
Bernhart, J. A., et al. (2022). The IMAGINE intervention. Translational Journal of the American College of Sports Medicine, 7(1), e000181. DOI: https://doi.org/10.1249/TJX.0000000000000181
Bradley, R. L., et al. (2008). Dietary fatty acids regulate TNF-alpha and IL-10. Obesity, 16(5), 938–944. DOI: https://doi.org/10.1038/oby.2008.39
Camargo-Ramos, C. M., et al. (2017). Dietary inflammatory index and cardiometabolic risk. International Journal of Environmental Research and Public Health, 14(10), 1104. DOI: https://doi.org/10.3390/ijerph14101104
Carey, C. C., et al. (2024). Exploring food choice influences in athletes. Proceedings of the Nutrition Society, 83(OCE4), E324. DOI: https://doi.org/10.1017/S0029665124005627
Chamberlin, M., et al. (2022). Inflammation variability and physical activity. Medicine & Science in Sports & Exercise, 54(9S), 356–357. DOI: https://doi.org/10.1249/01.mss.0000879512.28184.d6
Dave, A., et al. (2025). Evaluating anthropometric indices and inflammation. Indian Journal of Public Health.
Dion, S., et al. (2024). Diet quality of athletes. Nutrients, 16(24), 4317. DOI: https://doi.org/10.3390/nu16244317
Doustmohammadian, A., et al. (2024). Dietary inflammatory index and CRP. Clinical Nutrition ESPEN, 60, 156–164. DOI: https://doi.org/10.1016/j.clnesp.2024.01.017
Fisberg, R. M., & Villar, B. S. (2002). Manual de receitas e medidas caseiras. Signus.
Gleeson, M., et al. (2011). The anti-inflammatory effects of exercise. Nature Reviews Immunology, 11(9), 607–615. DOI: https://doi.org/10.1038/nri3041
Gleeson, M. (2013). Anti-inflammatory effects of exercise. Em A. Dannenberg & N. Berger (Eds.), Obesity, inflammation and cancer. Springer. DOI: https://doi.org/10.1007/978-1-4614-6819-6_16
Godala, M., et al. (2025). Pro-inflammatory diet and inflammatory bowel disease. Nutrients, 17(17), 2858. DOI: https://doi.org/10.3390/nu17172858
Hass, U., et al. (2022). Dietary inflammatory index and muscle function. Journal of Nutrition Health & Aging, 26(4), 346–351. DOI: https://doi.org/10.1007/s12603-022-1753-4
Jackson, A. S., & Pollock, M. L. (1978). Generalized equations for predicting body density of men. British Journal of Nutrition, 40(3), 497–504. DOI: https://doi.org/10.1079/BJN19780152
Jackson, A. S., et al. (1980). Generalized equations for predicting body density of women. Medicine and Science in Sports and Exercise, 12(3), 175–181. DOI: https://doi.org/10.1249/00005768-198023000-00009
Kęska, A., et al. (2022). Dietary inflammatory index in active men. International Journal of Environmental Research and Public Health, 19(11), 6884. DOI: https://doi.org/10.3390/ijerph19116884
Kosendiak, A., et al. (2023). Eating habits among ultrarunners. Frontiers in Nutrition, 10, 1137412. DOI: https://doi.org/10.3389/fnut.2023.1137412
Li, S., et al. (2025). Dietary inflammatory index and abdominal adipose tissue. Journal of Health, Population and Nutrition, 44, 254. DOI: https://doi.org/10.1186/s41043-025-00991-3
Matsudo, S., et al. (2001). Questionário internacional de atividade física. Revista Brasileira de Atividade Física e Saúde, 5, 5–18.
Millar, S. R., et al. (2022). Dietary score and chronic inflammation. European Journal of Nutrition, 61(7), 3377–3390. DOI: https://doi.org/10.1007/s00394-022-02892-1
Molina, M. C., et al. (2013). Validade do questionário de frequência alimentar. Cadernos de Saúde Pública, 29(6), 379–389. DOI: https://doi.org/10.1590/S0102-311X2013000600024
Muros, J. J., et al. (2021). Dietary habits in cyclists and triathletes. Scientific Reports, 11(1), 15193. DOI: https://doi.org/10.1038/s41598-021-94660-0
Ndiema, K. E. (2023). Mediterranean diet and inflammatory index. Nutrients, 15(2), 366. DOI: https://doi.org/10.3390/nu15020366
Passos, B. N., et al. (2019). Dietary intake and marathon inflammation. Mediators of Inflammation, 1537274. DOI: https://doi.org/10.1155/2019/1537274
Phillips, C. M., et al. (2017). Physical activity and inflammatory status. International Journal of Behavioral Nutrition and Physical Activity, 14(1), 1–12. DOI: https://doi.org/10.1186/s12966-017-0594-8
Pietrzak, A., et al. (2023). Diet inflammatory index in active individuals. Nutrients.
Proschinger, S., et al. (2023). Interval and continuous exercise effects on inflammation. European Journal of Applied Physiology.
Reihmane, D., & Dela, F. (2014). Interleukin-6 roles during exercise. European Journal of Sport Science, 14(3), 242–250. DOI: https://doi.org/10.1080/17461391.2013.776640
Rocha, D. M., et al. (2017). Dietary fatty acids and inflammatory gene expression. São Paulo Medical Journal, 135(2), 157–168. DOI: https://doi.org/10.1590/1516-3180.2016.008607072016
Shi, J., et al. (2023). Physical activity and dietary inflammatory index. Environmental Health and Preventive Medicine, 28, 40. DOI: https://doi.org/10.1265/ehpm.23-00016
Shin, P. K., et al. (2020). Korean diet and inflammatory markers. Nutrients, 12(8), 2468. DOI: https://doi.org/10.3390/nu12082468
Shivappa, N., et al. (2015). Dietary inflammatory index and inflammatory markers. British Journal of Nutrition, 113(4), 665–671. DOI: https://doi.org/10.1017/S000711451400395X
Shivappa, N., et al. (2014). Designing a dietary inflammatory index. Public Health Nutrition, 17(8), 1689–1696. DOI: https://doi.org/10.1017/S1368980013002115
Tabela Brasileira de Composição de Alimentos. (2023). Versão 7.2. Universidade de São Paulo.
Siri, W. E. (1961). Body composition from fluid spaces and density. Em Techniques for measuring body composition (pp. 223–244).
Via, J., et al. (2024). Exercise effects on immune function. Journal of Physiology. DOI: https://doi.org/10.1113/JP287173
Wang, H., et al. (2025). Anti-inflammatory diets and mortality. Nutrition & Metabolism, 22, 11. DOI: https://doi.org/10.1186/s12986-025-00907-2
Wang, X., et al. (2023). Dietary inflammatory index and depressive symptoms. Journal of Affective Disorders, 335, 332–339. DOI: https://doi.org/10.1016/j.jad.2023.05.012
Zhang, S., et al. (2023). Central obesity and inflammatory markers. International Journal of Environmental Research and Public Health, 20(5), 3781. DOI: https://doi.org/10.3390/ijerph20053781
Zhou, J., et al. (2025). Physical activity, inflammatory diet and diabetes. Nutrients, 17(1), 47. DOI: https://doi.org/10.3390/nu17010047