ACCIONES MUCOPROTECTORAS DE LA GOMA DE ANADENANTHERA COLUBRINA EN LA MUCOSITIS INTESTINAL EXPERIMENTAL
DOI:
https://doi.org/10.56238/arev7n11-394Palabras clave:
Quimioterapia, Inflamación, Fabaceae, Mucosa IntestinalResumen
La mucositis intestinal es uno de los principales efectos adversos asociados a la quimioterapia con el agente antineoplásico 5-fluorouracilo (5-FU), para el cual aún no existen terapias específicas disponibles, siendo su manejo predominantemente paliativo. En este contexto, los productos naturales han mostrado alternativas prometedoras para mitigar los efectos secundarios derivados del tratamiento oncológico. La goma de Anadenanthera colubrina (Vell.), conocida popularmente como “angico blanco”, es uno de estos compuestos naturales y se destaca por sus propiedades antimicrobianas, antiinflamatorias y antioxidantes previamente descritas. Este estudio tuvo como objetivo evaluar el potencial efecto protector de la goma de angico blanco, un heteropolisacárido obtenido del exudado de esta leguminosa, en un modelo experimental de mucositis intestinal inducida por 5-FU.
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