MUCOPROTECTIVE ACTIONS OF ANADENANTHERA COLUBRINA GUM IN EXPERIMENTAL INTESTINAL MUCOSITIS

Authors

  • Kezia de Souza Nunes Author
  • Laisa Divina Vieira Lavor Author
  • Fábio Muniz de Rezende Author
  • Daniel Correa de Vasconcelos Author
  • Michele Maia Assad Author
  • Vanessa Moraes da Silva Author
  • Kimberlly Menslin Pimenta Author
  • Yuri de Oliveira Frota de Siqueira Author
  • Rebeca Carolina Lira de Carvalho Otéro Author
  • Cintia da Silva Nascimento Author
  • Lorena Teles Paiva Author
  • Helder Bindá Pimenta Author

DOI:

https://doi.org/10.56238/arev7n11-394

Keywords:

Chemotherapy, Inflammation, Fabaceae, Intestinal Mucosa

Abstract

Intestinal mucositis is one of the main adverse effects associated with chemotherapy using the antineoplastic agent 5-fluorouracil (5-FU), for which there are still no specific therapies available, with management being predominantly palliative. In this context, natural products have shown promising alternatives in mitigating the side effects resulting from oncological treatment. The gum of Anadenanthera colubrina (Vell.)popularly known as "white angico" is one of these natural compounds, standing out for its previously described antimicrobial, anti-inflammatory, and antioxidant properties. This study aimed to evaluate the potential protective effect of white angico gum, a heteropolysaccharide obtained from the exudate of this legume, in an experimental model of 5-FU-induced intestinal mucositis.

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References

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Published

2025-11-30

Issue

Vol. 7 No. 11 (2025)

Section

Articles

How to Cite

NUNES, Kezia de Souza et al. MUCOPROTECTIVE ACTIONS OF ANADENANTHERA COLUBRINA GUM IN EXPERIMENTAL INTESTINAL MUCOSITIS. ARACÊ , [S. l.], v. 7, n. 11, p. e10574, 2025. DOI: 10.56238/arev7n11-394. Disponível em: https://periodicos.newsciencepubl.com/arace/article/view/10574. Acesso em: 5 dec. 2025.