BRAZILIAN BROWN PROPOLIS AGAINST ALZHEIMER'S DISEASE IN IN SILICO MODEL
DOI:
https://doi.org/10.56238/arev6n4-148Keywords:
Brown Propolis, Alzheimer's disease, Model in Silico, Antioxidant PropertiesAbstract
INTRODUCTION: Over the last few years, with the growth in quality of life and inversion of the age pyramid, an increase in the elderly population has brought a public health problem regarding diseases related to aging, especially neurodegenerative diseases (Domingos et al., 2018). Among the most common pathologies, Alzheimer's Disease (AD) is one of the most worrisome and has in its etiopathology the deposition of β-amyloid protein, hyperphosphorylation of the intraneuronal TAU protein, irreversible, neurodegenerative and progressive neuronal loss, and is clinically characterized by the impairment of cognitive and functional abilities along with behavioral changes (Scheltens et al., 2021).
