DIAGNOSIS OF TRAUMATIC SPINAL CORD INJURIES (SCI): INITIAL CLINICAL EVALUATION AND SYSTEMATIC NEUROLOGICAL EXAMINATION
DOI:
https://doi.org/10.56238/arev8n3-059Keywords:
Spinal Cord Injury, Traumatic Spinal Cord Injury, ISNCSCI, ASIA Scale, Surgical DecompressionAbstract
Spinal cord injury (SCI) is a high-impact neurological injury that results in permanent functional deficits and significant limitations in quality of life. A coordinated initial approach, starting with pre-hospital immobilization, is crucial. Diagnosis and prognostic stratification are fundamentally based on the application of the Systematized Neurological Examination, according to the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) or the American Spinal Injury Association (ASIA) scale. This protocol classifies injuries as complete (AIS A) and incomplete (AIS B to E), with incomplete injuries (especially C and D) associated with a greater potential for motor recovery in the first three to six months. The evaluation is complemented by neuroimaging, with computed tomography (CT) for bone assessment and magnetic resonance imaging (MRI) indispensable for the spinal cord parenchyma. Current clinical evidence strongly favors early surgical decompression (within 24 hours) to mitigate secondary damage. Adjuvant and regenerative therapies (such as riluzole and mesenchymal stem cells) are under investigation, and early rehabilitation, with the aid of technologies such as functional electrical stimulation (FES), is essential to optimize functional recovery and neuroplasticity. It is concluded that a systematic clinical assessment, integrated with neuroimaging, is the central pillar for therapeutic decision-making and optimization of prognosis in spinal cord injury (SCI).
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References
BYDON, M. et al. Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial. Nature Communications, v. 15, p. 2201, 2024.
CHEN, L. M. et al. Longitudinal Multiparametric MRI of Traumatic Spinal Cord Injury in Animal Models. Magnetic Resonance Imaging, v. 102, p. 184-200, 2023.
CHIKUDA, H. et al. Effect of Early vs Delayed Surgical Treatment on Motor Recovery in Incomplete Cervical Spinal Cord Injury With Preexisting Cervical Stenosis: A Randomized Clinical Trial. JAMA Network Open, v. 7, n. 2, p. e2356434, 2024.
CRYNS, N. et al. Clinical Practice Guideline: The Diagnosis and Treatment of Acute Spinal Cord Injury. Deutsches Ärzteblatt International, e-Supplement 2, 2024.
FEHLINGS, M. G. et al. Safety and Efficacy of Riluzole in Acute Spinal Cord Injury Study (RISCIS): A Multi-Center, Randomized, Placebo-Controlled, Double-Blinded Trial. Journal of Neurotrauma, v. 40, p. 1878-1888, 2023.
HERNANDEZ-NAVARRO, A. et al. Non-invasive cerebral and spinal cord stimulation for motor and gait recovery in incomplete spinal cord injury: systematic review and meta-analysis. Journal of NeuroEngineering and Rehabilitation, v. 22, p. 53, 2025.
IZZY, S. Traumatic Spinal Cord Injury. Continuum (Minneap Minn), v. 30, n. 1, p. 53-72, 2024.
KHADOUR, F. A. et al. Epidemiological features of traumatic spinal cord injury in Wuhan, China. Journal of Orthopaedic Surgery and Research, v. 18, p. 72, 2023.
KIRSHBLUM, S. et al. Characterizing Natural Recovery after Traumatic Spinal Cord Injury. Journal of Neurotrauma, v. 38, p. 1267-1284, 2021.