LUNG TRANSPLANTATION IN A PATIENT WITH ACUTE SILICOSIS: A CASE REPORT

Authors

  • Letícia Prieto Trindade Author
  • João Daniel Bringel Rego Author
  • Raquel Melo Nunes de Carvalho Author
  • Ana Carolina Gomes Siqueira Author
  • Jefferson Fontinele e Silva Author

DOI:

https://doi.org/10.56238/arev8n2-141

Keywords:

Silicosis, Respiratory Failure, Lung Transplantation

Abstract

Acute silicosis is a rare and rapidly progressive form of occupational lung disease resulting from intense exposure to free silica, commonly occurring in activities such as sandblasting and stone grinding. It is characterized by the accumulation of proteinaceous material within the alveoli, leading to severe respiratory failure and a poor prognosis, with possible progression to death within two years. Despite a reduction in cases due to advances in personal protective measures, it remains an important diagnostic and therapeutic challenge. The objective is to describe the clinical, diagnostic, and therapeutic course of a patient with acute silicosis who underwent bilateral lung transplantation, highlighting the importance of early recognition and timely referral to specialized lung transplant centers. The methodology is based on a case report developed through retrospective analysis of clinical, laboratory, radiological, histopathological, and follow- up data from a patient treated at a tertiary public hospital in the Federal District, Brazil. The information was obtained through electronic medical record review. The case demonstrates that lung transplantation may represent an effective therapeutic alternative in selected cases of acute silicosis, particularly in young patients, reinforcing the relevance of early diagnosis and occupational prevention.

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References

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Published

2026-02-28

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Articles

How to Cite

TRINDADE, Letícia Prieto; REGO, João Daniel Bringel; DE CARVALHO, Raquel Melo Nunes; SIQUEIRA, Ana Carolina Gomes; FONTINELE E SILVA, Jefferson. LUNG TRANSPLANTATION IN A PATIENT WITH ACUTE SILICOSIS: A CASE REPORT. ARACÊ , [S. l.], v. 8, n. 2, p. e12381 , 2026. DOI: 10.56238/arev8n2-141. Disponível em: https://periodicos.newsciencepubl.com/arace/article/view/12381. Acesso em: 24 mar. 2026.