IMPACT OF CANNABIDIOL ON GUIDED BONE REGENERATION: IMPLICATIONS FOR MODERN IMPLANTODONTICS
DOI:
https://doi.org/10.56238/levv16n52-046Keywords:
Cannabidiol, Guided Bone Regeneration, Implant Dentistry, Osteogenesis, BiomaterialsAbstract
Guided bone regeneration (GBR) is a widely used technique in implant dentistry to restore bone quantity and quality in areas with defects, aiming at implant success. In recent years, cannabidiol (CBD), a phytocannabinoid from Cannabis sativa, has shown promising therapeutic properties in regenerative processes due to its modulatory effects on inflammation, osteogenesis, and bone remodeling. This article presents a literature review of experimental and clinical studies on the effects of CBD on bone regeneration, analyzing its mechanisms of action, safety, efficacy, and potential applications in implant dentistry. Findings indicate that CBD promotes osteoblast differentiation, inhibits osteoclast activity, reduces inflammation, and enhances graft integration, creating a favorable environment for healing and implant success. Although results are promising, controlled clinical studies are needed to establish standardized therapeutic protocols and define safe doses. The incorporation of CBD in GBR represents an innovative perspective for personalized regenerative treatments, contributing to significant advances in modern implant dentistry.
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