Clinical manifestations and management of congenital Zika virus infection: A systematic review

Abstract

Objective: The general objective of the present study is to analyze the scientific production on Congenital Zika Virus Infection, seeking to identify the main clinical manifestations, as well as the main methods used in the treatment of this pathology. Methodology: It is a systematic review focused on understanding the main aspects of Congenital Zika Virus Infection. The research was guided by the question: "What are the main signs and symptoms of congenital Zika virus infection in the pediatric population, as well as what are the therapeutic resources used in clinical practice?" . To find answers, searches were performed in the PubMed database using three descriptors combined with the Boolean term "AND". This resulted in 010 articles. 12 articles were selected for analysis. Results: Congenital Zika syndrome (CZS) emerges as a complex and multifaceted challenge whose implications go beyond the boundaries of public health. Babies exposed to the Zika virus during pregnancy face a range of clinical manifestations, from microcephaly to eye anomalies and neurological disorders. Prevention, therefore, takes on a crucial role: educating pregnant women about the risks and promoting protective measures, such as the use of repellents and mosquito nets, is imperative. Conclusion: Although we do not yet have a licensed Zika vaccine, research efforts continue to explore this possibility. In addition, long-term surveillance is essential to fully understand the effects of the virus. In this scenario, awareness, interdisciplinary collaboration, and a commitment to the well-being of future generations are our best allies in the fight against this potentially devastating syndrome.