MICROBIOTA AND MIND: THE GUT-BRAIN AXIS AS A PATH TO WELL-BEING

Abstract

The gut microbiota has been widely studied for its role in overall health, including the influence on the central nervous system (CNS) through the microbiota-gut-brain axis. This research investigates the relationship between gut microbiota and mental health, highlighting how dysbiosis can contribute to psychiatric disorders such as depression and anxiety. The systematic review of the literature followed the PRISMA guidelines, analyzing studies on the influence of the microbiota on the production of neurotransmitters, on the modulation of the immune system, and on the regulation of the hypothalamic-pituitary-adrenal axis. Evidence indicates that modulation of the microbiota through probiotics and specific diets can help improve psychiatric symptoms. Despite the advances, there are still challenges in the standardization of interventions. Understanding the microbiota-gut-brain axis can offer new therapeutic perspectives for psychiatric disorders, promoting integrative approaches to mental health.