GENETIC SEQUENCING OF BRCA1 AND BRCA2 MUTATIONS AND CONDUCT, A REVIEW
INTRODUCTION: Breast cancer (BC) is a series of malignancies that affect the mammary gland, being the most common cancer in the world. In 2023, in Brazil, the incidence was 42 cases per 100,000 women. Modifiable risk factors include lifestyle, and non-modifiable risk factors include advancing age and genetic alterations, the main genes being BRCA1 and BRCA2. OBJECTIVE: This review aims to analyze the mutations of the main BC genes, BRCA1 and BRCA2, and their relevance in medical practice. METHODS: Articles in English and Portuguese published in the last 5 years in the PubMed and Scielo databases were selected using the keywords: breast cancer, genes, and BRCA1 and BRCA2. RESULTS: Data elucidate that approximately 5 to 10% of BC cases are related to heredity, and 30% of BC patients had a positive family history. These are tumor suppressor genes responsible for the correct processing of DNA strands. When these genes repair DNA strands improperly, apoptosis occurs, which is insufficient to contain potentially oncogenic multiplication. Furthermore, approximately 75% of mutations can occur throughout life due to lifestyle and vary according to penetrance. The two genes are the most relevant, since BRCA1 has a risk of developing breast cancer of about 57 to 65% and an estimated 20 to 50% risk of ovarian cancer. While for BRCA2 the estimates are 35 to 57% and 5 to 23%, respectively; moreover, they can favor oncogenesis in other locations such as the fallopian tubes, ovaries, peritoneum, and pancreas, and in BRCA2, also melanoma. The importance of identifying these mutations lies in the possibility of clinical repercussions, such as the decision to perform risk-reducing bilateral mastectomy, oophorectomy, or annual screening with magnetic resonance imaging or transvaginal ultrasound with annual or semi-annual Doppler Doppler, or chemoprophylaxis with Tamoxifen. Another application of genetic testing is the discussion about the use of platinum agents or polymerase inhibitors for cancer treatment, in addition to strategies such as risk-reducing contralateral mastectomy; due to these factors, the use of these tests has been increasing. CONCLUSION: In summary, breast cancer is the most common cancer in the world and is related to heredity and mutations in the BRCA1 and BRCA2 genes, which are tumor suppressors. Besides breast cancer, these genes cause neoplasms in other sites, and the recognition of their mutations allows for a better clinical approach in treatment. DOI: https://doi.org/10.56238/edimpacto2025.090-095
ADOPTION AND STRUCTURAL RACISM: THE INVISIBILITY OF BLACK CHILDREN IN THE FOSTER CARE SYSTEM AND THE NEED FOR AFFIRMATIVE ACTION POLICIES
The article addresses the impacts of structural racism in the context of adoption of Black children and adolescents in Brazil. The general objective is to investigate and demonstrate the intrinsic relationship between the selectivity in profile choices in the adoption process and the perpetuation of structural racism. The specific objectives are: to analyze the phenomenon of structural racism and its relationship with the adoption of Black children and adolescents in Brazil; and to analyze the invisibility of Black children and adolescents in the National Adoption System (SNA) through the lens of Structural Racism, demonstrating how the selectivity in the profiles desired by applicants, combined with institutional biases, compromises the effectiveness of the right to family coexistence for this portion of the child and youth population. The research problem seeks to investigate the following question: In what way does structural racism manifest itself in the selectivity of the desired profile by adoption applicants, impacting the realization of the right to family coexistence for Black children and adolescents in Brazil? The methodology employed in the study is based on a qualitative and exploratory research approach, utilizing bibliographical research techniques. DOI: https://doi.org/10.56238/edimpacto2025.090-094
DISSIDENT OLD AGE AND POLITICAL ABANDONMENT: A CRITICAL ANALYSIS OF MEDIA DISCOURSE ON LGBTQIA+ AGING
This article analyzes journalistic discourse on the aging of the LGBTQIA+ population in Brazil, with an emphasis on the systematic absence of representations of black gay men in old age. Based on a corpus composed of articles published between 2023 and 2025, a qualitative critical-interpretative approach is adopted, grounded in post-critical and decolonial paradigms. The method used is Critical Discourse Analysis, articulated with theoretical references on body, race, sexuality, and old age. The results show the operation of a programmed invisibility, sustained by discursive silences, deserotization, and affective-political abandonment. It is concluded that media discourses produce a regulated representation of LGBTQIA+ old age, excluding subjects who deviate from the white, cisgender, and heteronormative norm. The study points to the need to reconfigure epistemologies and discursive practices that recognize the centrality of black, dissident, and aging bodies in the production of memory, desire, and citizenship. DOI: https://doi.org/10.56238/edimpacto2025.084-026
"REVOLTA KIDS": A CHRONICLE OF A TRAGEDY FORETOLD ABOUT THE RIGHT TO CHILDHOOD AND INSTITUTIONAL CARE
This article discusses the realization of the right to childhood in the context of institutional care, in light of the Statute of Children and Adolescents (ECA) and historical-cultural theory. It starts from the understanding that institutionalization should be an exceptional and temporary measure, aimed at the integral protection and preservation of family and community ties. Bibliographic analysis and the report of professional experience reveal that, in practice, institutional care faces challenges related to the scarcity of resources, the fragmentation of public policies, and the absence of significant affective bonds, elements that directly impact the emotional and social development of children. Episodes such as the so-called "Kids' Revolt" show that behaviors interpreted as indiscipline can represent expressions of suffering, fear, and a search for recognition. It is observed that the role of professionals, especially pedagogues and social educators, is fundamental for the construction of humanized relationships that consider the child as a historical subject and a subject of rights. It is concluded that guaranteeing the right to childhood in institutional care requires intersectoral actions, qualified training, and educational practices that promote affection, listening, and continuity in relationships. DOI: https://doi.org/10.56238/edimpacto2025.092-075
Carla Adriane Leite Arrieira Spaciari Machado
PLAYFULNESS AND TECHNOLOGIES: GAMIFICATION IN SUPPORT OF THE INCLUSION OF STUDENTS WITH AUTISM SPECTRUM DISORDER IN ELEMENTARY EDUCATION
Playfulness is part of children's daily lives. From a very early age, students are introduced to games and toys as a form of distraction and entertainment. However, the didactic and pedagogical value of playfulness in the school environment cannot be ignored. In this perspective, this study had as its general objective to investigate how playfulness, through gamification, can contribute to the inclusion of students with Autism Spectrum Disorder (ASD) in Elementary School. The specific objectives included: investigating the theoretical foundations related to playfulness and its relevance in the inclusion process; identifying the main needs related to the teaching and learning process of students with ASD; and identifying different gamification strategies and their applications to create a more inclusive learning environment for students with ASD in Elementary School. To this end, a bibliographical research was carried out, based on the review of theoretical literature on playfulness, gamification, and school inclusion processes for students with ASD. The criteria adopted were: studies published in the last ten years and that were relevant to a better understanding of the phenomenon investigated through the research. The results indicate that gamification, by incorporating game elements into the school environment, favors engagement, motivation and the development of social and emotional skills of students with ASD. This approach creates more welcoming environments, facilitating communication, social interaction and the understanding of complex content in an accessible and enjoyable way. It is concluded that playfulness, especially through gamification, has great potential to promote inclusion, meeting the specific needs of these students and valuing their uniqueness. The implementation of gamified strategies, combined with inclusive pedagogical practices, can transform the school environment into a more motivating, collaborative and accessible space, contributing significantly to the comprehensive development of students with ASD. DOI: https://doi.org/10.56238/edimpacto2025.092-074
DEMOCRATIC AND PARTICIPATORY SCHOOL MANAGEMENT: PATHWAYS TO BUILDING CITIZEN AND INCLUSIVE SCHOOLS
This study examines democratic and participatory school management as a fundamental axis for building inclusive and citizenship-oriented schools committed to the integral development of students. The research highlights that democratic management goes beyond administrative tasks, assuming pedagogical, political, and collective dimensions. Based on authors such as Libâneo, Lück, Paro and Gadotti, the study analyzes the principles of participation, autonomy, collegiality, and pedagogical leadership, emphasizing the crucial role of school principals as mediators and coordinators of collective work. It also discusses the importance of school councils, the collaborative development of the political-pedagogical project, and the strengthening of participatory culture to ensure transparency, shared responsibility, and social quality in education. The study concludes that democratic school management requires the articulation of legal frameworks, inclusive practices, community participation, and ongoing professional development, becoming an essential path for transforming the school into a space of citizenship, equity, and human development. DOI: https://doi.org/10.56238/edimpacto2025.090-093
HISTORY OF HISTORY TEACHING IN BRAZIL: FROM THE CONSTRUCTION TO THE RECONSTRUCTION OF THE DISCIPLINARY CODE
This article analyzes the historical development of History teaching in Brazil, focusing on the processes of construction and reconstruction of its disciplinary code over the centuries. From a theoretical-critical perspective, it discusses the curricular transformations, educational reforms, and ideological disputes that have shaped the discipline from the colonial period to the implementation of the National Common Curricular Base (BNCC). The study examines the role of official guidelines, school culture, textbooks, and public policies in defining teaching content and methods, highlighting continuities and disruptions that have influenced pedagogical practices. The article emphasizes the importance of adopting a plural, critical, and inclusive approach that acknowledges Brazil's cultural diversity and fosters active citizenship. By problematizing the tensions between tradition and innovation, the work contributes to the ongoing debate on the direction of history education in the country, pointing to the challenges and possibilities of building a more reflective and democratic pedagogical practice. DOI: https://doi.org/10.56238/edimpacto2025.090-092
PHYTOSANITARY STRUCTURE AND EPIDEMIOLOGICAL PATTERNS OF PLANT DISEASES IN AN AGROECOSYSTEM OF THE BRAZILIAN CERRADO
Plant diseases are one of the main limiting factors of agricultural productivity in tropical regions, due to the interaction between pathogens, hosts, and environmental conditions favorable to the development of epidemics. In this context, the present study aimed to carry out a phytosanitary mapping of diseases in tropical crops cultivated at the State University of Goiás, South Campus, Ipameri University Unit, identifying the main etiological agents, the predominant symptoms, and the environmental factors associated with their occurrence. The survey was conducted through systematic zigzag walking in three areas with different land uses, characterizing itself as observational and descriptive. The identification of diseases was based on symptomatological analysis in the field and on specialized phytopathological literature. The results showed a high diversity of diseases, with a predominance of fungal pathogens, highlighting genera such as Colletotrichum, Corynespora, Pseudocercospora, and Septoria, in addition to the recurrent occurrence of parasitic algae. Functional convergence of damage was observed, mainly associated with the formation of necrotic lesions and a reduction in the active photosynthetic area, regardless of the specific causal agent. The absence of systematized phytosanitary management favored the persistence of the inoculum and increased the local epidemiological risk. It is concluded that systematic phytosanitary surveys constitute a strategic tool for phytosanitary surveillance, supporting integrated disease management and the sustainability of tropical agroecosystems. DOI: https://doi.org/10.56238/edimpacto2025.090-091
Ellen Jardyelle de Carvalho da Conceição
FRUGAL INNOVATION IN TEACHING PRACTICE FOR YOUTH AND ADULT EDUCATION: INCLUSION OF AUTISTIC ADULTS IN CONTEXTS OF SCARCITY
This article analyzes the emergence of Frugal Innovation in the teaching practice of Youth and Adult Education (EJA) as a pedagogical strategy for the inclusion of adults with Autism Spectrum Disorder (ASD) in contexts marked by resource scarcity. This is a qualitative study of a theoretical-analytical nature, based on a critical narrative review of national and international literature on EJA, inclusive education, Frugal Innovation, and simple educational technologies. The results show that, in the face of structural precariousness, the fragility of public policies, and the insufficiency of specific teacher training, EJA teachers develop creative pedagogical practices based on the use of accessible and low-cost technologies, configuring legitimate processes of Frugal Innovation. Such practices broaden the participation, autonomy, and engagement of autistic adults, while simultaneously challenging normative curricula and denouncing the naturalization of educational precariousness. It is concluded that Frugal Innovation, far from replacing public policies, constitutes a form of curricular resistance ethically committed to social justice, neurodiversity, and the right to lifelong education. DOI: https://doi.org/10.56238/edimpacto2025.090-090
Maryane Francisca Araujo de Freitas Cavalcante
Miranísia Aparecida de Araujo Freitas Lopes
THE USE OF PODCASTS AS A TEACHING RESOURCE IN DISTANCE EDUCATION: CONTRIBUTIONS TO MEANINGFUL LEARNING, DIGITAL LITERACY, AND STUDENT EMPOWERMENT
The transformations brought about by digital technologies have significantly impacted educational processes, especially in the context of Distance Education (DE), which is consolidating itself as a strategic modality for democratizing access to education. In this scenario, it becomes essential to reflect on pedagogical resources capable of promoting not only access to content, but also engagement, autonomy, and meaningful learning for students. Podcasts, as a widely disseminated digital sound medium in contemporary culture, present themselves as a promising tool for technology-mediated educational practices. This article aims to analyze the use of podcasts as a didactic resource in DE, discussing its potential and limitations with regard to meaningful learning, digital literacy, and student protagonism. Methodologically, this is a qualitative, exploratory, and descriptive research, based on a bibliographic review of authors who discuss Distance Education, active methodologies, digital literacy, and educational media. The results indicate that podcasts promote flexible access to knowledge, encourage authorship practices, and strengthen student engagement, provided they are integrated into intentional pedagogical planning and critically mediated by the teacher. It is concluded that podcasts are consolidating themselves as an innovative and strategic resource for distance education, articulating technology, language, and education in more inclusive, collaborative, and meaningful formative experiences. DOI: https://doi.org/10.56238/edimpacto2025.092-073
THE REFINEMENT OF PRECARIOUS WORK AND EDUCATION AS EXPRESSED BY THE RE-SABER SYSTEM
This article analyzes the Re-Saber Program, established by MEC Ordinance No. 24 of January 19, 2021. The analysis of the legal framework of Re-Saber does not commit to raising the educational level of participants and relegates to a secondary position the articulation of experiential knowledge with scientific knowledge for the population destined for the most precarious work, underemployment, informality, and outsourcing. In this sense, the Re-Saber Program, by making training more precarious, contributes to the dismantling of access, retention, and academic success, while co-opting education workers into this project under the guise of being efficient, flexible, and amplifying the professional/individual status of its base team; and, lastly, it takes advantage of this opportunity to increase statistics on certification in institutions (number of enrolled students, certificates, etc.), under the pretext that there is a commitment from the State to education and to workers. DOI: https://doi.org/10.56238/edimpacto2025.092-072
THE CHEMISTRY BEHIND CLEANING PRODUCTS: TEACHING ACID-BASE REACTIONS, STOICHIOMETRY, AND CHEMICAL BONDS THROUGH EXPERIMENTATION
Although it is a fundamental science for areas such as medicine and industry, the teaching of Chemistry is still dominated by a traditional model centered on the memorization of formulas, rules, and nomenclature, generally without connection to the social reality of the students. Working with the 1st year class of the technical course in Roads at the Federal Institute of Alagoas - Maceió Campus, it was found that many students viewed Chemistry as something abstract. Therefore, the PIBID scholarship holders intervened, with the support of the supervising teacher, introducing experimental practices for the production of cleaning products and corroborating the classes with the subjects of stoichiometry, inorganic functions, and chemical bonds. The analysis of the students' reports revealed that the experimental practices favored the conceptual, functional, and integrated appropriation of chemical content, frequently addressed in an abstract way in high school. DOI: https://doi.org/10.56238/edimpacto2025.090-089
Samuel Anderson Calheiros da Silva Siqueira
VEREDAS: CHARACTERIZATION, DISTRIBUTION AND IMPORTANCE
Veredas are unique formations found only in Brazil. They are a typical vegetation formation of the Cerrado. Although still little known, they contain endemic fauna and flora species. They are characterized not only by the outcrop of the aquifer, but also by soil type, phytophysiognomy, and species present. Since the first Brazilian Forest Code, veredas have been permanent preservation areas. The Forest Code establishes that veredas are considered permanent preservation areas, with a marginal strip of 50 meters from the permanently marshy or wetland area. Despite their relevance and importance, they still present problems related to conservation, demarcation, and disorderly land use and occupation. DOI: https://doi.org/10.56238/edimpacto2025.090-088
BETWEEN CHANCE AND INTENTION: ROAD TRAFFIC AS AN INVISIBLE SPACE OF SUICIDE
Traffic accidents are among the leading causes of preventable death worldwide and are traditionally interpreted as unintentional events resulting from human error, environmental conditions, or infrastructure deficiencies. However, scientific evidence indicates that a proportion of these deaths may correspond to intentional or semi-intentional suicidal behaviors, which are frequently rendered invisible and recorded as accidents of undetermined cause. This study aims to critically analyze the scientific evidence on the phenomenon of hidden suicide in the context of traffic, examining the relationship between suicidal ideation, risky driving behaviors, limitations in death classification systems, and implications for road safety. This is an integrative narrative review of the literature, qualitative and analytical-interpretative in nature, based on classic and contemporary studies published in national and international databases. The findings indicate recurring patterns associated with intentionality, such as single-vehicle collisions, high speed, absence of evasive maneuvers, and the selection of highly lethal scenarios, as well as a consistent association between suicidal ideation and risky driving behaviors. It is concluded that the statistical invisibility of suicide in traffic compromises epidemiological surveillance and limits preventive strategies, reinforcing the need for intersectoral approaches that integrate road safety, mental health, and public policies aimed at preventing avoidable deaths. DOI: https://doi.org/10.56238/edimpacto2025.089-009
INTENSIVE CARE NURSING AND INNOVATION IN PATIENT SAFETY PROTOCOLS
The overall objective of this research is to discuss the role of intensive care nursing in relation to critical patient safety protocols. This is a narrative review, in which the articles were found in the Google Scholar repository. Patient safety in ICUs demands rigorous protocols, continuing education, and strategic action from intensive care nursing. Technological and team failures are avoidable with training and systematization of practices. DOI: https://doi.org/10.56238/edimpacto2025.078-002
HUMAN MILK AND HUMAN MILK BANKS: ADVANCES, CHALLENGES, AND INNOVATIONS IN NEONATAL FOOD CONSERVATION AND SAFETY
Human milk is recognized as the gold standard of neonatal nutrition, especially for premature newborns, due to its nutritional composition and numerous bioactive components with immunological, anti-inflammatory, and metabolic functions. In this context, Human Milk Banks (HMBs) play a fundamental role in promoting, protecting, and supporting breastfeeding, as well as in the collection, processing, quality control, and safe distribution of donated human milk. This study consists of a narrative literature review aiming to analyze the composition and benefits of human milk, the importance of breastfeeding in premature infants, the role of HMBs, and the conservation methods used, with an emphasis on emerging technologies such as lyophilization. The search was conducted in the PubMed, SciELO, and Google Scholar databases, including articles published between 1980 and 2024. The analyzed studies show that, although Holder pasteurization is effective in ensuring microbiological safety, it can partially compromise heat-sensitive components of human milk. In this scenario, lyophilization emerges as a promising alternative, capable of extending the stability, shelf life, and preservation of the bioactive properties of human milk, as well as facilitating storage and distribution. It is concluded that human milk banks remain essential pillars of neonatal public health and that investment in technological innovation, combined with scientific research, is strategic for optimizing the conservation and utilization of donated human milk. DOI: https://doi.org/10.56238/edimpacto2025.077-001
MEGADIVERSE COUNTRIES: AN INTEGRATIVE MULTIVARIATE ANALYSIS OF SPECIES RICHNESS, ITS DRIVERS, AND CONSERVATION CHALLENGES IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT GOAL 15 – LIFE ON LAND
Megadiverse countries harbor the majority of the world’s biological diversity and play a pivotal role in achieving global biodiversity conservation goals. This study presents a comprehensive multivariate analysis of species richness across vascular plants and vertebrate groups in twenty megadiverse countries, examining the ecological, geographical, climatic, and evolutionary drivers underlying their exceptional biodiversity. Using comparative data on species richness, land area, and multivariate ordination techniques, we identify patterns linking tropical and subtropical climates, habitat heterogeneity, historical biogeography, and isolation processes to high levels of biodiversity and endemism. The results highlight that species richness is not strictly proportional to country size, as smaller tropical nations such as Ecuador and Malaysia exhibit disproportionately high biodiversity densities. In addition to identifying biodiversity patterns, this study discusses the major conservation challenges faced by megadiverse countries, including deforestation, habitat fragmentation, climate change, and unsustainable resource use. Framed within the context of Sustainable Development Goal 15 (Life on Land), the findings emphasize the critical importance of megadiverse countries for global biodiversity conservation and the urgent need for integrated, socially inclusive, and sustainable conservation strategies aligned with the objectives of the 2030 Agenda. DOI: https://doi.org/10.56238/edimpacto2025.088-003
INNOVATION ECOSYSTEMS: A COMPARATIVE ANALYSIS OF THE MAPPING OF ACTORS BY SEBRAE IN PIAUÍ AND THE MIT IECOSYSTEMS MODEL
Innovation ecosystems have emerged as important elements for driving economic and social development in different regions. A precise understanding of the actors and actions that constitute these ecosystems is essential to guide effective policies and strategies for promoting innovation and entrepreneurship. This research aims to analyze the congruence between the actors in the local innovation ecosystem mapped by Sebrae Piauí and the MIT iEcosystems model. To this end, specific objectives were also carried out, such as identifying new actors in the state's local innovation ecosystem and evaluating the scope and representativeness of the actors mapped by Sebrae Piauí in relation to the components identified in the MIT iEcosystems model. It was concluded that the congruence between the elements and inputs of the iEcosystems methodology and the actors mapped by Sebrae is, in general, strong, with each element finding an appropriate counterpart among the actors from Sebrae. However, there are some gaps, especially in the specific details of governance and some more granular aspects of innovation and entrepreneurship that could be the subject of deeper analysis. DOI: https://doi.org/10.56238/edimpacto2025.070-006
Maryane Francisca Araújo de Freitas Cavalcante
AGE AND WEIGHT AT FIRST SERVICE OF THE GILT TO IMPROVE HER LIFETIME PERFORMANCE
Swine farms show greater reproductive efficiency due to improvements in ovulation rate and litter size; however, they require a constant supply of replacement gilts because of the persistently high culling rates (40 to 50%) of sows in the breeding herd. It is recommended that gilts be selected from third-parity litters, with birth weights above 1.2 kg, achieving growth rates of 600 g/day at 140 days of age and 650 to 750 g/day at the time of first service. From 140 days of age onward, stimulation with a mature boar should begin for 15 to 20 minutes in the morning and afternoon to induce puberty between 150 and 180 days of age. Gilts should be first serviced when they reach a body weight of 135 to 150 kg, with at least 13 mm of backfat thickness (BFT), generally at the second or third estrus, around 210 to 240 days of age. Servicing gilts at a body weight between 135 and 150 kg allows them to reach approximately 180 kg at first farrowing and to have a short weaning-to-estrus interval (WEI) of 3 to 6 days, with sufficient body reserves (15–18 mm BFT) to achieve a high ovulation rate, sustain pregnancy, and produce a large litter at the second farrowing. Gilts that are too old (>250 days) and overweight at first service are at increased risk of premature culling. Premature culling is mainly due to reproductive failures and locomotor problems, although an increase in mortality rate has also been recently reported. Sows with extended reproductive longevity are often characterized by producing large litters in their first two parities. To determine the economically optimal parity at culling, the cumulative number of piglets born and weaned during the sow’s productive life in the breeding herd and the future productive potential of a replacement gilt should be considered. For a gilt to be economically profitable, she needs to achieve three to four parities, with at least 12 piglets weaned per litter. DOI: https://doi.org/10.56238/edimpacto2025.073-002
PHYSICAL SYSTEMS MODELING - RLC CIRCUIT GRAPHICAL SIMULATOR
This article presents the user manual for the application entitled: Modelagem de Sistemas Físicos - Simulador Gráfico de Circuitos RLC (SimuRLC), developed to assist students in the field of Electrical and Electronic Engineering in understanding the mathematics for analyzing RLC circuits and the application of the Laplace Transformation involved in the process. This topic is highly relevant in the current context of accelerated digital transformation, where connectivity and the advancement of the Internet are key-factors. In the industrial sector, this evolution requires the use of mathematical models as a tool to face challenges in production environments more efficiently. The manual is divided into stages: (i) Application installation; (ii) Presentation of the Laplace Transformation used; (iii) Presentation of the application interface; (iv) Case study of a circuit applied in the application; (v) Graphical validation via LTspice®. The results obtained through simulations in the application, when compared to other software, indicate good agreement and numerical stability. The conclusions obtained offer important contributions to the academic field, providing useful information for the resolution and analysis for passive RLC circuits. DOI: https://doi.org/10.56238/edimpacto2025.086-005
ADAPTING CASHEW COOPERATIVES TO FAIR TRADE PRINCIPLES
Cashew cooperatives, when trading in the international market, seek to change their management oriented towards obtaining Fairtrade Labeling Organization International (FLO) certification. Therefore, the general objective is to analyze the adequacy of the cooperatives of the Central de Cooperativas de Cajucultores do Estado do Piauí - COCAJUPI in the almond production segment to the principles of fair trade that propagates social, economic and environmental benefits. The study methodology used field research, applying forms and unsystematic non-participatory observation, with reference to the principles of fair trade endorsed by FLO; and, secondary sources related to the theme. The research universe consisted of cooperatives linked to COCAJUPI, in which presidents-directors were interviewed in four cities. The results show that cooperatives, when adapting their production process to FLO principles, achieved greater financial gains by valuing their product, in addition to social improvements in compliance with labor standards in mini-factories, although the internal environment of cooperatives did not generate total comfort. to employees. In the environmental scope, the effects were timid, related to end-of-pipe techniques, such as rationalization of inputs, highlighting that there was still no eco-awareness of managers. It was concluded that the cooperatives affiliated with COCAJUPI adapted their production process and obtained the Fair Trade seal, generating economic and social advantages. However, the need to maintain a continuous learning process is paramount, in order to sustain, efficiently, the fulfillment of these requirements in the mini-factories. DOI: https://doi.org/10.56238/edimpacto2025.080-011
CULTIVATION OF LUDWIGIA PERUVIANA IN SOIL WITH HIGH LEVELS OF NICKEL
This study evaluated the cultivation of Ludwigia peruviana in soil contaminated with nickel (Ni), a heavy metal (HM) micronutrient that is toxic in high concentrations. Excess nickel poses risk to both human health and the environment. Five conditions were evaluated using different proportions of contaminated soil and substrate (0:100, 25:75, 50:50, 75:25, and 100:0), with ten replicates per treatment and one plant per pot. The cultivation period lasted 14 weeks in a greenhouse under controlled temperature and humidity conditions. Throughout the experiments, plant growth and chlorophyll content were monitored weekly, while flower production was recorded daily. At the end of the experiment, root length, total dry mass, and metal concentrations in different plant tissues were analyzed. Results indicated that L. peruviana exhibited low Ni uptake, accumulating only small amounts in the roots under lower Ni contamination levels. Additionally, exposure to excess Ni negatively affected plant growth, sprouting, chlorophyll content, total dry mass, root length, and reproductive development. These findings suggest that L. peruviana is not suitable for the phytoremediation of Ni-contaminated areas. However, due to its ability to thrive in compacted and nutrient-poor soils, this species may still be valuable as a bioindicator and for revegetation programs in degraded areas. DOI: https://doi.org/10.56238/edimpacto2025.080-010
SHADOW ZONES IN THE HEART OF AGRIBUSINESS: MOBILE INFRASTRUCTURE PRECARIOUSNESS AND THE PRODUCTIVE BOTTLENECK IN CAMPO NOVO DO PARECIS-MT
Mobile connectivity has become an essential input for the competitiveness of agribusiness cities, supporting everything from logistics to precision agriculture. This study diagnoses the telecommunications infrastructure in the municipality of Campo Novo do Parecis-MT, analyzing whether the supply of services keeps pace with the expansion of local development vectors. A quantitative descriptive approach was adopted, measuring the "Quality of Experience" (QoE) through a survey with 402 inhabitants. The results reveal a scenario of structural saturation and spatial selectivity: critical "shadow zones" were identified precisely in strategic production hubs (Industrial District) and human capital formation centers (IFMT), validating the theory of digital bypass. Demographic analysis pointed out that the active workforce (35-44 years old) is the most dissatisfied group (mean 1.57/5.0), indicating that network instability acts as a bottleneck to local productivity. Furthermore, the technological obsolescence of the network was noted, failing to support data-intensive demands (streaming/gaming), generating a high volume of complaints with low resolution. It is concluded that the telecommunications infrastructure has not kept up with the city's economic growth, requiring regulatory intervention to mitigate digital exclusion in functional areas. DOI: https://doi.org/10.56238/edimpacto2025.080-009
ARTIFICIAL INTELLIGENCE IN AGRICULTURE 4.0: ANT COLONY APPLIED TO WATER AND NITROGEN OPTIMIZATION
This study investigates Ant Colony Optimization (ACO) as an Artificial Intelligence strategy for the joint economic tuning of water and nitrogen in iceberg lettuce and melon crops, within the Agriculture 4.0 framework. Well-established agronomic production functions from the literature are replicated and embedded in a transparent two-dimensional grid formulation, in which pheromone deposition is proportional to performance and global evaporation controls the balance between exploration and intensification. The analysis focuses on solution quality, convergence dynamics, and sensitivity to key algorithm parameters and grid resolution. The economic optima obtained with ACO are consistent with results reported for existing AI/optimization-based tools and methods (such as INTELIAGRI, MBL, and Pattern Search), including a case in which the optimum lies on the boundary of the decision domain. Net revenues are computed under a uniform economic scenario, ensuring comparability across crops and approaches. The paper concludes by summarizing practical configuration guidelines for ACO and discussing their implications for the design of decision support systems in Agriculture 4.0 aimed at efficient water and nitrogen management. DOI: https://doi.org/10.56238/edimpacto2025.080-008
Thiago Marlon da Conceição Esteves Damas
HEALTH SCENARIO REGARDING THE CARE OF CHILDREN AFTER HOSPITALIZATION: A CROSS-SECTIONAL STUDY
Considering the challenges faced by parents or guardians after a child's hospital discharge, especially regarding continuity of care, medication administration, procedures, and monitoring for possible complications, a relevant problem emerges in the context of child health care. Added to this context is the influence of factors such as social support, resource availability, and the participation of health professionals in the home care process. Therefore, this study aims to understand the continuity of care and follow-up of children after hospitalization. To this end, a descriptive, cross-sectional study with a quantitative approach was conducted at the Child Health Clinic of a University Center in the Metropolitan Region of Recife, Pernambuco. The research involved the voluntary participation of 50 families of children followed at the institution. Among these children, 72% were male and 28% were female, predominantly in the 2-month to 1-year age range, with a length of stay between 1 and 10 days. It was also identified that the caregivers had low levels of education, lacked a fixed income, and had no formal employment. This study concluded that the post-hospital discharge period demanded significant support from families, highlighting the importance of public policies, health education initiatives, and strengthening multidisciplinary follow-up to ensure the continuity and quality of childcare. DOI: https://doi.org/10.56238/edimpacto2025.087-030
MEDICINAL PLANTS IN THE PROMOTION OF QUALITY SLEEP AND THE IMPROVEMENT OF HEALTH AND WELL-BEING
Sleep is a fundamental pillar of health, essential for tissue repair, emotional regulation, and metabolic balance. Sleep deprivation, a common problem in contemporary society, is associated with increased risks of obesity, diabetes, cardiovascular diseases, and mental disorders. The circadian rhythm, primarily regulated by light, orchestrates this process, and its disruption by modern lifestyle habits compromises health. Given this complexity, an integrative approach that considers the individual as a whole has gained relevance. In Brazil, the National Policy on Integrative and Complementary Practices (PNPIC) incorporates therapies such as phytotherapy, integrating scientific and traditional knowledge. Medicinal plants such as chamomile, passionflower, lemon balm, and mulungu emerge as allies in improving sleep quality, with scientifically studied mechanisms of action that modulate the GABAergic system (a calming neurotransmitter) and cortisol (the stress hormone). Scientific evidence supports the safe and effective use of these plants in the form of teas (infusions or decoctions), with specific preparation methods and precautions. However, it is important to emphasize that phytotherapy is a complementary intervention and does not replace medical evaluation. Its use should be integrated into conscious lifestyle changes, including regular schedules, exposure to natural light, and stress management, always under professional guidance. Thus, reconciling science and traditional wisdom through the simplicity of tea consumption can become a therapeutic ritual for reconnecting with the natural cycles of life and promoting restorative sleep. DOI: https://doi.org/10.56238/edimpacto2025.087-029
VAGINAL INFECTIONS: A NARRATIVE REVIEW OF THE MAIN VULVOVAGINITIDES
Vulvovaginitis is among the leading causes of gynecological consultations, affecting women across different age groups and significantly impacting quality of life. The most frequent etiologies include vulvovaginal candidiasis, bacterial vaginosis, and vaginal trichomoniasis, which account for the majority of symptomatic cases. This chapter aims to conduct a narrative review of these infections, addressing their main etiological agents, clinical manifestations, diagnostic methods, and therapeutic updates. Vulvovaginal candidiasis is predominantly caused by Candida albicans, although non-albicans species are associated with recurrent cases and greater antifungal resistance. Bacterial vaginosis is characterized by dysbiosis of the vaginal microbiota, often related to Gardnerella vaginalis, and may occur asymptomatically. Vaginal trichomoniasis, caused by Trichomonas vaginalis, is a highly prevalent sexually transmitted infection with important repercussions for sexual and reproductive health. Diagnosis of these conditions is based on clinical–laboratory correlation, with molecular methods representing more sensitive alternatives, although still limited by cost. Treatment involves specific antifungal, antibiotic, and antiparasitic agents, with growing concern regarding high recurrence rates and drug resistance. Therefore, the importance of accurate diagnosis, individualized management, and the development of new therapeutic strategies to optimize women’s health care is emphasized. DOI: https://doi.org/10.56238/edimpacto2025.087-028
PALLIATIVE CARE IN PATIENTS WITH METASTATIC CANCER: CHALLENGES FOR QUALITY OF LIFE
Palliative care constitutes an essential approach in the care of patients with metastatic cancer, with the primary focus on promoting quality of life through the relief of suffering and comprehensive attention to physical, emotional, social, and spiritual needs. In view of disease progression and the limitation of curative therapeutic possibilities, it becomes imperative to adopt strategies that prioritize patient comfort, dignity, and autonomy. This study aimed to analyze the challenges related to the promotion of quality of life in patients with metastatic cancer receiving palliative care, in light of public health policies and available scientific evidence. This is an integrative literature review conducted based on scientific studies and national and international normative documents selected from relevant health databases. The analysis of the results showed that patients’ quality of life is influenced by multiple factors, notably inadequate control of pain and other physical symptoms, the presence of emotional distress, weaknesses in family support, and limitations in the organization of the healthcare network. Additionally, the late introduction of palliative care and insufficient professional training were observed to compromise the effectiveness of care. It is concluded that palliative care has significant potential to improve the quality of life of patients with metastatic cancer when implemented in an early, continuous, and integrated manner, in accordance with current public health policies. Strengthening continuing health education and articulation among levels of care is essential for improving palliative care within the Unified Health System. DOI: https://doi.org/10.56238/edimpacto2025.091-045
Kharlo Emmanuely Gonçalves de Oliveira e Silva
EDUCATIONAL TECHNOLOGIES IN THE PREVENTION AND MANAGEMENT OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS
The chapter entitled “Educational Technologies in the Prevention and Management of Cardiovascular Risk in Diabetic Patients” presents a narrative review that synthesized evidence from articles retrieved from the SciELO, PubMed, and LILACS databases, as well as official documents from the Brazilian Ministry of Health and guidelines from the Brazilian Diabetes Society (SBD), published between 2007 and 2023. The selection prioritized three interconnected thematic axes: primary health care (PHC) and comprehensive care for diabetic patients; cardiovascular complications associated with diabetes mellitus (DM) and risk stratification methods; and the use of educational and digital technologies to support self-care and patient empowerment. Within PHC, DM represents a growing epidemiological challenge, with care pathways within the Brazilian Unified Health System (SUS) emphasizing early diagnosis, glycemic monitoring, and health education through the Family Health Strategy. Quality indicators show advances in access to supplies; however, gaps in treatment adherence persist, highlighting the need for innovative interventions. DM increases cardiovascular risk by up to fourfold. Strict therapeutic targets guide pharmacological treatment combined with secondary prevention strategies, such as lifestyle modifications. Educational technologies emerge as validated tools to promote behavioral change, telemonitoring, and patient empowerment, aligned with the principles of the SUS. Strategies aimed at strengthening care for diabetic patients should be further researched and developed in order to minimize the increasing prevalence of the disease, its complications, the loss of patients’ quality of life, and financial costs to the public health system. DOI: https://doi.org/10.56238/edimpacto2025.087-027
VULVOVAGINAL CANDIDIASIS: UPDATES ON DIAGNOSTIC AND TREATMENT APPROACHES
Vulvovaginal candidiasis (VVC) is one of the most frequent gynecological infections, affecting approximately 70% of women at some point in their lives and representing the second leading cause of vaginitis. It is mainly caused by Candida albicans; however, non-albicans species, which are more resistant to azoles, have increased in prevalence in recent decades, making clinical management more challenging. Clinically, VVC manifests with intense pruritus, burning sensation, dyspareunia, and thick white vaginal discharge. Despite its typical presentation, these symptoms have low predictive value and may be confused with other forms of vulvovaginitis, highlighting the need for laboratory confirmation. Diagnosis should include direct microscopy and mycological culture (gold standard), especially in recurrent or refractory cases. Molecular methods, such as PCR, have stood out for their high sensitivity and specificity, particularly in detecting non-albicans species, although they still face limitations related to cost and availability. VVC can be classified as uncomplicated (mild, sporadic episodes, usually caused by C. albicans and with good therapeutic response) or complicated, which includes resistant species, severe symptoms, pregnancy, comorbidities, immunosuppression, and recurrent vulvovaginal candidiasis (RVVC), defined as ≥4 episodes within one year. Treatment of uncomplicated VVC may be carried out with topical antifungals or oral fluconazole, both showing similar cure rates. In recurrent cases, prolonged fluconazole therapy is recommended (induction followed by maintenance for six months). The emergence of azole resistance has stimulated the development of new antifungal agents, such as ibrexafungerp. Partner treatment is only indicated when symptoms are present. VVC negatively impacts quality of life, affecting self-esteem, sexuality, and mental health, reinforcing the importance of accurate diagnosis, professional guidance, and individualized management. The article concludes that laboratory and therapeutic updates are essential to reduce recurrences and improve treatment effectiveness. DOI: https://doi.org/10.56238/edimpacto2025.087-026