THE ROLE OF CANNABIDIOL IN THE TREATMENT OF ATHEROSCLEROSIS: THERAPEUTIC POTENTIALS AND REGULATORY CHALLENGES IN MEDICINE

Abstract

Introduction: Cardiovascular diseases are one of the main causes of global mortality, and atherosclerosis, characterized by the accumulation of fatty plaques in the arteries, is one of the most common variants. Recently, Cannabidiol has sparked interest as a potential preventive approach to atherosclerosis. Objective: The present study aims to explore the therapeutic potential of Cannabidiol in this context, reviewing relevant clinical and experimental studies, in order to promote an interdisciplinary dialogue between researchers and health professionals. Methodology: For this, the PubMed Advanced database was used to conduct a literature review, with specific inclusion criteria that aimed to find direct studies on the therapeutic use of Cannabidiol in atherosclerosis. Results: The results highlight Cannabidiol's ability to reduce inflammation and mitigate complications associated with atherosclerosis, such as endothelial dysfunction and myocardial infarction. However, despite the promising findings, validating the efficacy and safety of Cannabidiol requires rigorous clinical trials. Conclusion: The study concluded that Cannabidiol demonstrates great potential as a therapeutic agent for atherosclerosis, and therefore, more research should be done on this substance so that we can fully use and understand its effects.