SICKLE CELL DISEASE: CLINICAL PROFILE AND DIAGNOSTIC AND DISEASE CONTROL INSTRUMENTS

Abstract

The objective of the present study is to present evaluative instruments as a proposal to outline the clinical profile of people with Sickle Cell Disease (SCD). The descriptive study was conducted based on the analysis of clinical trials, reports, guidelines, literature reviews, and available evidence about the most commonly used instruments for measuring pain, quality of life, anxiety, depression, fatigue, and sociodemographic aspects of people with SCD. The clinical profile can be performed through detailed anamnesis with sociodemographic information; pain measurement using the Visual Analogue Scale (VAS) and Brief Pain Inventory (BPI); determining quality of life using the Short Form Health Survey (SF-36); prevalence of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS); and determining the degree of fatigue using the Patient-Reported-Outcome Measurement Information System – Fatigue (PROMIS). The search for detailed information on the evaluative instruments used to outline the clinical profile is relevant because it will provide adequate guidance for the follow-up and treatment of SCD.