LICHEN EXTRACTS FROM PARMOTREMA SPECIES DO NOT EXHIBIT ACARICIDAL EFFECTS ON RESISTANT RHIPICEPHALUS MICROPLUS LARVAE
DOI:
https://doi.org/10.56238/arev7n12-083Keywords:
Bioprospection, Cattle Tick, Cerrado, Liquenized Fungi, Parmeliaceae, Secondary MetabolitesAbstract
Lichens, symbiotic associations between a mycobiont and a photosynthetic partner, produce a wide range of secondary metabolites with documented antifungal, antibacterial, anti-inflammatory, anticoagulant, and antiparasitic properties. Within this group, the family Parmeliaceae is one of the most diverse, and several of its species are known to synthesize biologically active lichen acids. To evaluate the potential acaricidal activity of these compounds, methanolic and hexanic extracts were prepared from the thallus most abundant Parmotrema (P. latissimum, P. mesotropum, and P. rubifaciens) species collected in the Cerrado areas of Itaguatins/ Tocantins, Brazil. Biological activity was assessed through larval immersion assays following Klafke (2006), using resistant larvae of Rhipicephalus microplus (Jaguar strain) exposed to extract concentrations ranging from 0.4 to 2.0 mg/ML, serial dilutions. Under the conditions tested, all extracts exhibited 0% larval mortality, indicating an absence of acaricidal activity against the resistant tick lineage at the evaluated concentrations.
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