CASE REPORT: IGA VASCULITIS
DOI:
https://doi.org/10.56238/arev7n12-050Keywords:
Henoch-Schönlein Purpura, Vasculitis, Petechiae, ChildhoodAbstract
Henoch-Schönlein purpura is a leukocytoclastic vasculitis characterized by the deposition of IgA1 immunoglobulin, leading to vascular necrosis. Consequently, multiple organ systems may be affected, including the skin, joints, gastrointestinal tract, and kidneys. This case report describes a 4.6-year-old preschooler who initially presented with otalgia, followed by petechiae on the lower limbs and hips, and subsequently developed abdominal pain. Initial treatment consisted of an antibiotic combined with a proton pump inhibitor. However, due to clinical worsening, pulse therapy with methylprednisolone was initiated, resulting in a successful outcome and improvement of the previously reported symptoms.
Downloads
References
1.Nikolaishvili M, Pazhava A, Di Lernia V. Viral Infections May Be Associated with Henoch–Schönlein Purpura. Journal of Clinical Medicine [Internet]. 2023 Jan 1 [cited 2023 Feb 16];12(2):697. Available from: https://www.mdpi.com/2077-0383/12/2/697 DOI: https://doi.org/10.3390/jcm12020697
2.Ekinci RMK, Balci S, Melek E, Karabay Bayazit A, Dogruel D, Altintas DU, et al. Clinical manifestations and outcomes of 420 children with Henoch Schönlein Purpura from a single referral center from Turkey: A three-year experience. Modern Rheumatology. 2019 Nov 14;30(6):1039–46. DOI: https://doi.org/10.1080/14397595.2019.1687074
3.Federica Di Vincenzo, Ennas S, Pizzoferrato M, Stefano Bibbò, Porcari S, Ianiro G, et al. Henoch–schonlein purpura following exposure to SARS-CoV2 vaccine or infection: a systematic review and a case report. Internal and emergency medicine. 2023 Jul 27;19(1):13–37. DOI: https://doi.org/10.1007/s11739-023-03366-w
4.Leung AKC, Barankin B, Leong KF. Henoch-Schönlein purpura in children: an updated review. Current Pediatric Reviews. 2020 May 8;16(4). DOI: https://doi.org/10.2174/15733963MTA2FNDYc2
5.Jedlowski PM, Jedlowski MF. Coronavirus disease 2019‐associated immunoglobulin A vasculitis/Henoch–Schönlein purpura: A case report and review. The Journal of Dermatology. 2021 Nov 5;49(1):190–6. DOI: https://doi.org/10.1111/1346-8138.16211
6.Asiri A, Alzahrani F, Alshehri S, Hassan AbdelQadir Y. New-Onset Henoch–Schonlein Purpura after COVID-19 Infection: A Case Report and Review of the Literature. Kasapcopur O, editor. Case Reports in Pediatrics. 2022 Mar 29;2022:1–5. DOI: https://doi.org/10.1155/2022/1712651
7.Jacobi M, Lancrei HM, Tal Brosh-Nissimov, Yonatan Yeshayahu. Purpurona: A Novel Report of COVID-19-Related Henoch-Schonlein Purpura in a Child. The Pediatric Infectious Disease Journal [Internet]. 2020 Nov 16 [cited 2025 Feb 25];40(2):e93–4. Available from: https://journals.lww.com/pidj/fulltext/2021/02000/purpurona__a_novel_report_of_covid_19_related.30.aspx?context=featuredarticles. DOI: https://doi.org/10.1097/INF.0000000000003001
8.João de Almeida Sant’Ovaia M. Púrpura de Henoch Schonlein: a propósito de um caso clínico [Internet]. ulisboa.pt. universidade de lisboa; 2021 [cited 2025 Feb 2]. Available from: https://repositorio.ulisboa.pt/bitstream/10451/52585/1/ManuelJSantOvaia.pdf
9.Negri MB, Rabelo T, Nascimento LP, Alves NC, Medeiros JS. Lesões hemorrágicas vesico-bolhosas na púrpura de henoch-schönlein e revisão da literatura. Journal Archives of Health. 2024 Jul 12;5(3):e1762–2. DOI: https://doi.org/10.46919/archv5n3espec-089
10.Faria LO de, Cabral LPC, Neto FI de A, Santana RKM de BNM de, Santos AC, Guareschi CP, et al. Púrpura de Henoch Schonlein - Relato de Caso/ Henoch Schonlein’s Purpura - Case Report. Brazilian Journal of Health Review [Internet]. 2021 Oct 13 [cited 2024 Jul 7];4(5):21711–24. Available from: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/37265 DOI: https://doi.org/10.34119/bjhrv4n5-259
11.Gomes C, Cruz, Moraes I, Campos H, Freitas GA, Cesar F, et al. Análise da incidência e fatores predisponentes para recorrência da Púrpura de Henoch-Schönlein em pacientes pediátricos. E-Acadêmica. 2022 Oct 28;3(3):e3233311–1. DOI: https://doi.org/10.52076/eacad-v3i3.311
12.Penido MGMG, Palma LMP. IgA vasculitis in children. Jornal Brasileiro De Nefrologia: 'Orgao Oficial De Sociedades Brasileira E Latino-Americana De Nefrologia [Internet]. 2022 Jan 1;44(1):3–5. Available from: https://pubmed.ncbi.nlm.nih.gov/35312744/#
