OVARIAN HYPERSTIMULATION SYNDROME: A CONSEQUENCE OF EXCESSIVE HORMONE USE
DOI:
https://doi.org/10.56238/zarev7n11-021Keywords:
Assisted Reproduction, In vitro Fertilizatio, HormonesAbstract
Infertility affects approximately 25% of couples of reproductive age, making assisted reproduction a fundamental alternative for achieving pregnancy. Among the available techniques, in vitro fertilization (IVF) stands out for the use of hormones that stimulate follicular development and favor embryonic implantation. However, ovarian stimulation may trigger Ovarian Hyperstimulation Syndrome (OHSS), an iatrogenic complication associated with the use of gonadotropins. This descriptive and qualitative study aimed to analyze the implications of hormone use in the gestational process of assisted human reproduction, particularly those associated with OHSS. To this end, a critical review of the literature published between 2015 and 2025 was conducted, addressing the physiological effects of hormones employed in IVF and their clinical repercussions. The findings indicate that the hormonal response to ovarian stimulation involves endocrine, metabolic, and cardiovascular alterations that may compromise the safety and efficacy of treatment. Preventive strategies such as individualized protocols based on biomarkers (AMH, body weight, and ovarian reserve), the use of GnRH agonists, and strict clinical monitoring significantly reduce the incidence and severity of OHSS. It is concluded that the personalization of hormonal protocols and continuous monitoring are essential to optimize reproductive outcomes, minimize risks, and promote a safer and more effective approach to assisted reproduction.
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