A PRODUÇÃO AGRÍCOLA DA CANNABIS VISANDO O AUMENTO DO TEOR DE CANABIDIOL (CBD) PARA FIM MEDICINAL – REVISÃO
DOI:
https://doi.org/10.56238/arev7n12-128Palavras-chave:
Cannabis, Produção Agrícola, CanabidiolResumo
A Cannabis sativa Linnaeus é uma planta herbácea, da família Cannabaceae. Suas inflorescências femininas são ricas em tricomas glandulares, que possuem metabólitos secundários com propriedades medicinais, como o canabidiol (CBD). A carência de informações sobre o manejo do cultivo da Cannabis para fins biomédicos dificulta o desenvolvimento de uma produção de qualidade e padronizada. Buscou-se na literatura estudos com intervenções no cultivo da Cannabis visando a melhoria do teor de CBD para fim medicinal. Pesquisou-se sistematicamente no Portal de Periódicos da CAPES> Acervo> Assunto>, com o termo de busca Cannabis and Crop production, com filtro em artigos de acesso aberto, originais, em inglês, revisado por pares. Incluiu-se artigos científicos contendo práticas de cultivo da Cannabis, quimiotipo III em pertinência ao objetivo. Foram excluídos artigos de produção agrícola da Cannabis sem fim medicinal, artigo de revisão, estudos não científicos, THC > 0,3%, sem melhoramento de CBD, sem análise instrumental do teor de CBD e Cannabis Quimiotipo I e II. A busca resultou em 09 artigos elegíveis, com as seguintes intervenções: manipulação das concentrações de fósforo; densidade de semeadura e a fertilização com nitrogênio; aplicação do antagonista de auxina em condições in vitro; seleção de cultivares, práticas agronômicas otimizadas em ambiente de cultivo controlado; manipulação estratégica do espectro de luz; topping; tratamento com 6-benzilaminopurina (BAP); seleção de cultivares e manejo hídrico; material geneticamente uniforme em diferentes condições ambientais. Para maior êxito no aumento do CBD sem o aumento do THC é primordial a escolha da cepa Quimiotipo III para fim medicinal.
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