KETOGENIC DIET AND CORTISOL MODULATION: BENEFITS FOR STRESS MANAGEMENT

Abstract

The ketogenic diet, composed of high lipid content, moderate protein intake, and severe carbohydrate restriction, has stood out not only in the treatment of refractory epilepsy, but also as a possible ally in stress control and cortisol modulation, a key hormone in the response to chronic stress. Based on a narrative review of the literature, this study sought to analyze the effects of this nutritional strategy on neuroendocrine regulation, highlighting the production of ketone bodies, especially beta-hydroxybutyrate, as a central element for the benefits observed in emotional stability and symptoms related to anxiety and depression. In addition, the influences of diet on the hypothalamic-pituitary-adrenal axis, the impacts on oxidative stress and the clinical aspects relevant to its application were addressed. The findings indicate that the ketogenic diet, when well conducted, can represent a promising complementary intervention in the management of stress-related conditions, contributing to the promotion of well-being and mental health.