PERSONALIZED APPROACHES TO METABOLIC TREATMENT IN PATIENTS WITH COMPLEX COMORBIDITIES

Abstract

Metabolic diseases associated with complex comorbidities represent a growing challenge for contemporary clinical practice, requiring therapeutic strategies that take into account the clinical, nutritional, and functional heterogeneity of patients. This study aimed to analyze, through a bibliographic review, the main personalized approaches applied to metabolic treatment in patients with multiple comorbidities, considering their impacts on metabolic control, body composition, and clinical outcomes. The methodology consisted of a qualitative, descriptive, and exploratory study based on a critical analysis of national scientific literature related to the topic. The results indicate that personalized approaches, especially those integrating individualized nutritional therapy, multicomponent interventions, and continuous clinical monitoring, show greater effectiveness in metabolic management when compared to generalized strategies. It was observed that considering factors such as body composition, nutritional status, and functionality contributes to improved clinical outcomes, reduced complications, and greater treatment adherence. It is concluded that personalized metabolic treatment represents a fundamental strategy for the care of patients with complex comorbidities, promoting greater therapeutic precision, improved quality of life, and optimization of healthcare resources.