CHILDHOOD DEPRESSION: THERAPEUTIC MANAGEMENT STRATEGIES

Authors

  • Ryan Rafael Barros de Macedo Author
  • Pedro Medeiros Barreto Campello Author
  • Júlia Dal Bó Cassettari Author
  • Deborah Cristina Silva Nascimento Author
  • Aline Araujo Alves Author
  • Hyuri Vasconcelos Feliciano Pereira Author
  • Gabriela de Paiva Gonçalves Author
  • Anna Paula de Souza Santos Author

DOI:

https://doi.org/10.56238/levv16n55-143

Keywords:

Childhood Depression, Adolescence, Cognitive Behavioral Therapy, Selective Serotonin Reuptake Inhibitors, Therapeutic Management, Child and Adolescent Mental Health

Abstract

Depression in childhood and adolescence is a debilitating clinical condition that affects between 10% and 20% of the global youth population, severely impacting academic and social development. This narrative review analyzes contemporary therapeutic management strategies, highlighting the multifactorial nature of the disease, which involves everything from neurobiological dysregulation (HPA axis and BDNF) to dietary and inflammatory influences. Evidence suggests that psychotherapy, especially Cognitive Behavioral Therapy (CBT) and Interpersonal Therapy (IPT), is the first line of treatment for mild to moderate cases. In severe cases, pharmacotherapy with Selective Serotonin Reuptake Inhibitors (SSRIs)—such as fluoxetine—is indicated under strict monitoring. The review also addresses innovations such as digital interventions, music therapy, and nutritional supplementation (omega-3), reinforcing the need for a multidisciplinary and personalized approach to mitigate the risk of suicide and recurrence in adulthood.

Downloads

Download data is not yet available.

References

BUTTAZZONI, A. et al. Intervenções baseadas em smartphones e transtornos internalizantes em jovens: revisão sistemática e meta-análise. Journal of Medical Internet Research, v. 23, n. 1, p. 16490, 2021.

BRITO, Helton Djohnsons Silva; PORCINO, José Marciel Araújo; ALVES, Carmen Silva. INTERVENÇÕES BASEADAS NA TERAPIA COGNITIVO-COMPORTAMENTAL NO ACOLHIMENTO DE ADOLESCENTES PÓS-TENTATIVA DE SUICÍDIO EM UM CAPS INFANTIL: uma proposta de cuidado em saúde mental. Revista Multidisciplinar do Nordeste Mineiro, [S.L.], v. 20, n. 1, p. 1-31, 10 nov. 2025. AlfaUnipac. http://dx.doi.org/10.61164/d5db4k20.

FREITAS, Victoria Andrade Solano Rodriguez; NUNES, Paulo Barbosa; ARAÚJO, Alanna Viana; SOUZA, Julliane Ketly Magalhães de; CARNEIRO, Lorena; SANTOS, Yasmim Nunes. DEPRESSÃO INFANTIL: SINAIS PRECOCES, BARREIRAS NO DIAGNÓSTICO E ABORDAGENS TERAPÊUTICAS ATUAIS. Revista Ibero-Americana de Humanidades, Ciências e Educação, [S. l.], v. 11, n. 4, p. 2731–2739, 2025. DOI: 10.51891/rease.v11i4.18861. Disponível em: https://periodicorease.pro.br/rease/article/view/18861. Acesso em: 22 dez. 2025.

LIMA, M. O. F. F. et al. Depression and Anxiety Symptoms in Children: Associations with Family Functioning. Psicologia: ciência e profissão, v. 44, p. 1-13, 2024.

LÓPEZ-SOLER, C. et al. Effectiveness of internet-delivered psychological treatments for children and adolescents with anxiety and/or depressive disorders: Systematic review and network meta-analysis. International journal of clinical and health psychology, v. 24, n. 3, p. 100487, 2024.

KRAUSE, K. R. et al. Comparative effectiveness of distinct digital treatment delivery methods for child and adolescent depression: a systematic review and network meta-analysis. EClinicalMedicine, v. 53, p. 101666, 2022.

PARK, J.-I. Evidence-based non-pharmacological treatment for child and adolescent depression. Journal of the Korean Medical Association, v. 62, n. 11, p. 577-584, 2019.

PARK, J. -I. et al. Effects of music therapy as an alternative treatment on depression in children and adolescents with ADHD by activating serotonin and improving stress coping ability. BMC Complementary Medicine and Therapies, v. 23, n. 1, p. 73, 2023.

PONTES, E. R. et al. Children and Adolescents with Depression: Perception of Family Caregivers. Psychology of Health, v. 33, p. 3312, 2023.

SIGRIST, C.; AMMANN, R. A. Treatment of depression in children and adolescents. Paediatrica, v. 32, n. 2, p. 1-6, 2021.

SILVA, J. S. et al. Estratégias e implicações no manejo terapêutico do quadro depressivo na infância e juventude. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 5, p. 1568-1590, 2024.

WITT, K. G. et al. Interventions for self-harm in children and adolescents. Cochrane Database of Systematic Reviews, n. 3, CD013667, 2021.

ZIELIŃSKA, M. et al. Current Treatment Options in Major Depressive Disorder in Adolescents. International Journal of Environmental Research and Public Health, v. 18, n. 21, p. 11432, 2021.

ZWOLIŃSKA, W. et al. Treatment of Depressive Disorders in Children and Adolescents. Postępy Higieny i Medycyny Doświadczalnej, v. 77, p. 16-25, 2023.

Published

2025-12-29

How to Cite

DE MACEDO, Ryan Rafael Barros; CAMPELLO, Pedro Medeiros Barreto; CASSETTARI, Júlia Dal Bó; NASCIMENTO, Deborah Cristina Silva; ALVES, Aline Araujo; PEREIRA, Hyuri Vasconcelos Feliciano; GONÇALVES, Gabriela de Paiva; SANTOS, Anna Paula de Souza. CHILDHOOD DEPRESSION: THERAPEUTIC MANAGEMENT STRATEGIES. LUMEN ET VIRTUS, [S. l.], v. 16, n. 55, p. e11482, 2025. DOI: 10.56238/levv16n55-143. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/11482. Acesso em: 30 mar. 2026.