Metachronous colorectal tumor of atypical location: Case report

Abstract

Colorectal cancer and esophageal cancer are distinct malignancies, but they share risk factors and mechanisms of carcinogenesis. Colorectal cancer, originating in the colon or rectum, is characterized by the uncontrolled growth of epithelial cells, and has a high global incidence, being the third most common and the second leading cause of cancer death. In 2022, Brazil recorded 13,921 deaths from this neoplasm, with a higher prevalence in people over 50 years of age, especially from the age of 70. Esophageal cancer, responsible for about 0.54 million deaths annually and the eighth most common cause of cancer, manifests as squamous cell carcinomas or adenocarcinomas and is strongly associated with family history, smoking, and alcohol consumption. Both types of cancer involve cellular dysfunction and resistance to apoptosis, and share risk factors such as male gender and family history, although there is no direct relationship between them.