AESTHETIC CHALLENGES POST-TIRZEPATIDE: INNOVATIVE APPROACHES TO GLUTEAL PTOSIS WITH POLYMETHYL METHACRYLATE
DOI:
https://doi.org/10.56238/ERR01v10n6-063Keywords:
Tirzepatide, Gluteal Ptosis, Polymethylmethacrylate (PMMA)Abstract
Introduction: Tirzepatide, a dual GLP-1 and GIP receptor agonist, has demonstrated superior efficacy in obesity treatment, promoting significant and accelerated weight loss. However, the rapid weight reduction induced by this therapy can lead to aesthetic complications such as gluteal ptosis, characterized by volume loss and skin laxity. Objective: To report a case of severe gluteal ptosis developed after tirzepatide-induced weight loss and to describe an innovative and successful treatment protocol using polymethylmethacrylate (PMMA). Methodology: This is a clinical case report of a 36-year-old female patient who presented with marked gluteal ptosis following a 10 kg weight loss in less than 30 days with tirzepatide use. Treatment consisted of the combined application of 200 mL of 30% PMMA in the intramuscular plane and 30 mL of 15% PMMA in the superficial subcutaneous plane, in each gluteus. Free and informed consent was obtained for data publication. Results: The patient showed satisfactory clinical evolution, with significant restoration of gluteal contour and notable improvement in skin laxity. No adverse events were recorded during the follow-up period, and the outcome provided a recovery of self-esteem and aesthetic satisfaction. Conclusion: The therapeutic protocol employing PMMA in different concentrations and anatomical planes proved to be a safe and effective approach for correcting gluteal ptosis resulting from rapid weight loss induced by tirzepatide. This technique represents a minimally invasive alternative for managing the aesthetic sequelae of pharmacologically assisted weight loss, emphasizing the importance of aesthetic consideration in obesity treatment.
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