TREATMENT FOR VITILIGO WITH A COMPOUNDED FORMULATION CONTAINING TOPICAL ANTI-INFLAMMATORY DRUGS: CASE REPORT

Abstract

Introduction: Vitiligo is a dermatological condition that causes white spots on the skin due to the loss of melanocytes. Classified as an autoimmune disease, it is associated with genetic and environmental factors, and oxidative stress. It occurs predominantly in people aged between 10 and 30 years, affecting the self-esteem and quality of life of patients. Objective: This study aimed to follow a patient using a manipulated formulation containing topical anti-inflammatory drugs, regarding the improvement in the pigmentation of the spots. Case Report: The volunteer presented vitiligo spots in the eye ~]area and eyelid, leading to self-esteem problems because they are very visible spots. The formulation containing topical anti-inflammatory drugs was manipulated at a Compounding Pharmacy in the city of Maringá (PR) and delivered to the volunteer, with instructions for use for application once a day directly on the spots, always at night, after cleaning the affected region.  The students were monitored weekly, through photos and the application of a questionnaire to the volunteer. The treatment was carried out for 30 days, without any complications, discomfort or skin irritation. The patient reported having undergone the treatment without interruption, and, after the total treatment time, there was a significant improvement in pigmentation. In the questionnaire applied, the volunteer reported that there was an improvement in the appearance of the spots, and the result can be observed in the weekly photos. This research was approved by the Ethics Committee for Research with Human Beings of Uningá (CEP/Uningá), under protocol number 6,950,683.