GLUCOCORTICOID-INDUCED OSTEOPOROSIS

Abstract

Cushing's Syndrome (CS) is a disorder caused by excess cortisol in the blood, which can be exogenous (due to the use of glucocorticoids) or endogenous (due to dysfunctions in the adrenal glands or pituitary gland). This condition is associated with several morbidities, including hypertension, visceral obesity and, especially, osteoporosis, caused by the inhibition of the function of osteoblasts, responsible for bone formation. The narrative review seeks to understand the relationship between the prolonged use of glucocorticoids and the development of osteoporosis.