DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS OF THE INCIDENTAL DETECTION OF RENAL MASSES: A LITERATURE REVIEW

Authors

  • Beatriz Cruz de Paula Author
  • Débora Vieira Nogueira Author
  • Ian Lucas de Oliveira Author
  • Augusto Castelli von Atzingen Author

DOI:

https://doi.org/10.56238/levv17n60-060

Keywords:

Diagnostic Imaging, Kidney Neoplasms, Incidental Findings, Tomography, X-Ray Computed, Magnetic Resonance Imaging

Abstract

INTRODUCTION: Considering the progressive increase in the incidental detection of renal masses due to the widespread use of abdominal imaging exams for the investigation of nonspecific complaints, a significant shift in the presentation profile of renal neoplasms has been observed, with greater identification of asymptomatic lesions at early stages. This study aims to analyze the diagnostic implications of the incidental identification of these masses and to discuss their influence on defining the clinical approach. METHODOLOGY: A literature review was conducted using the PubMed, Scielo, and Google Scholar databases, applying descriptors related to the topic and previously established inclusion criteria. RESULTS AND DISCUSSION: An expressive proportion of renal carcinomas is diagnosed incidentally, expanding the possibilities for conservative interventions and nephron-sparing surgeries. Furthermore, contemporary diagnosis relies predominantly on imaging methods, which are essential for lesion characterization and differentiation between benign and malignant processes. However, incidental detection may also include indolent tumors and benign lesions, requiring careful evaluation to avoid excessive therapeutic interventions. CONCLUSION: The incidental identification of renal masses has relevant diagnostic and therapeutic implications, making the proper interpretation of radiological findings essential to guide individualized and rational clinical management.

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References

BAZZOCCHI, M. V. et al. The role of CT imaging in characterization of small renal masses. Diagnostics, Basel, v. 13, n. 3, p. 334, jan. 2023. DOI: 10.3390/diagnostics13030334. Disponível em: https://doi.org/10.3390/diagnostics13030334 DOI: https://doi.org/10.3390/diagnostics13030334

BELLIN, M.-F. et al. Update on Renal Cell Carcinoma Diagnosis with Novel Imaging Approaches. Cancers, v. 16, n. 10, p. 1926, 18 maio 2024. DOI: https://doi.org/10.3390/cancers16101926

CHARTIER, Stephane; ARIF-TIWARI, Hina. MR virtual biopsy of solid renal masses: an algorithmic approach. Cancers, v. 15, n. 10, p. 2799, 2023. DOI: https://doi.org/10.3390/cancers15102799 DOI: https://doi.org/10.3390/cancers15102799

GUTIÉRREZ HIDALGO, Beatriz; GÓMEZ RIVAS, Juan; DE LA PARRA, Irene; MARUGÁN, María Jesús; SERRANO, Álvaro; HERMIDA GUTIÉRREZ, Juan Fco.; BARRERA, Jerónimo; MORENO-SIERRA, Jesús. The use of radiomic tools in renal mass characterization. Diagnostics, v. 13, n. 17, p. 2743, 2023. DOI: https://doi.org/10.3390/diagnostics13172743 DOI: https://doi.org/10.3390/diagnostics13172743

McGough WC, Sanchez LE, McCague C, Stewart GD, Schönlieb CB, Sala E, Crispin-Ortuzar M. Artificial intelligence for early detection of renal cancer in computed tomography: A review. Camb Prism Precis Med. 2022 Nov 11;1:e4. doi: 10.1017/pcm.2022.9. PMID: 38550952; PMCID: PMC10953744. DOI: https://doi.org/10.1017/pcm.2022.9

Rose TL, Kim WY. Renal Cell Carcinoma: A Review. JAMA. 2024 Sep 24;332(12):1001-1010. doi: 10.1001/jama.2024.12848. PMID: 39196544; PMCID: PMC11790279. DOI: https://doi.org/10.1001/jama.2024.12848

Silvestri A, Gavi F, Sighinolfi MC, Assumma S, Panio E, Fettucciari D, Pallotta G, Schubert O, Carerj C, Ragonese M, Russo P, Bientinesi R, Foschi N, Ciccarese C, Iacovelli R, Rocco B. Management of Small Renal Masses: Literature and Guidelines Review. Int Braz J Urol. 2025 Sep-Oct;51(5):e20250203. doi: 10.1590/S1677-5538.IBJU.2025.0203. PMID: 40339174; PMCID: PMC12539897. DOI: https://doi.org/10.1590/s1677-5538.ibju.2025.0203

SHANG, Wenwen; HONG, Guohui; LI, Wei. MRI for the detection of small malignant renal masses: a systematic review and meta-analysis. Frontiers in Oncology, v. 13, p. 1194128, 2023. DOI: https://doi.org/10.3389/fonc.2023.1194128 DOI: https://doi.org/10.3389/fonc.2023.1194128

Twardy S, Zepeda S, Kumar H. Massive Renal Cyst Presenting With Chest Pain and Gastrointestinal Symptoms. Cureus. 2025 Aug 5;17(8):e89442. doi: 10.7759/cureus.89442. PMID: 40918834; PMCID: PMC12410981. DOI: https://doi.org/10.7759/cureus.89442

TROVATO, P. et al. Scientific Status Quo of Small Renal Lesions: Diagnostic Assessment and Radiomics. Journal of clinical medicine, v. 13, n. 2, p. 547–547, 18 jan. 2024. DOI: https://doi.org/10.3390/jcm13020547

TSILI, A. C. et al. The role of imaging in the management of renal masses. European Journal of Radiology, v. 141, p. 109777, ago. 2021. DOI: https://doi.org/10.1016/j.ejrad.2021.109777

URRARO, Fabrizio; PISCOPO, Marco; GIORDANO, Nicoletta; RUSSO, Gaetano Maria; GALLO, Luigi; MAGLIOCCHETTI, Simona; GIORDANO, Diego Sandro; PATANÈ, Vittorio; ARCANIOLO, Davide; COZZOLINO, Immacolata; et al. Diagnostic value of contrast-enhanced ultrasound in differentiating malignant from benign small renal masses after CT/MRI. Journal of Clinical Medicine, v. 13, n. 21, p. 6478, 2024. DOI: https://doi.org/10.3390/jcm13216478 DOI: https://doi.org/10.3390/jcm13216478

‌Woon D, Qin S, Al-Khanaty A, Perera M, Lawrentschuk N. Imaging in Renal Cell Carcinoma Detection. Diagnostics (Basel). 2024 Sep 23;14(18):2105. doi: 10.3390/diagnostics14182105. PMID: 39335784; PMCID: PMC11431198. DOI: https://doi.org/10.3390/diagnostics14182105

Published

2026-05-23

How to Cite

DE PAULA, Beatriz Cruz; NOGUEIRA, Débora Vieira; DE OLIVEIRA, Ian Lucas; VON ATZINGEN, Augusto Castelli. DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS OF THE INCIDENTAL DETECTION OF RENAL MASSES: A LITERATURE REVIEW. LUMEN ET VIRTUS, [S. l.], v. 17, n. 60, p. e13218, 2026. DOI: 10.56238/levv17n60-060. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/13218. Acesso em: 29 may. 2026.