PROTOCOLS FOR THE MANAGEMENT OF PEDIATRIC ORAL MUCOSITIS

Authors

  • Chiara Ulhiana Cypriani da Silva Author
  • Maely Alves de Medeiros Author
  • Geovanna Maria Ramos Porto de Souza Author
  • Amanda Marques Ribeiro Author
  • Eduardo Loures Filho Author
  • Maria Láysi Santana dos Santos Author
  • Pedro Kaique Coelho Feitosa Author
  • Rafael Amaral Oliveira Author

DOI:

https://doi.org/10.56238/levv17n59-009

Keywords:

Oral Mucositis, Pediatric Patients, Oncology, Photobiomodulation, Honey

Abstract

Oral mucositis is an inflammatory and ulcerative process of the oral mucosa, considered one of the most frequent complications in pediatric patients undergoing cancer treatments. This study aimed to synthesize and analyze the most recent scientific evidence related to management protocols for oral mucositis in pediatrics. It consists of a narrative literature review, conducted in the PubMed database and scientific repositories. The results demonstrated that physical, phytotherapeutic, and pharmacological interventions were able to reduce severe lesions, control pain, inflammation, and healing time. These findings point to effective protocols that allow for the management of mucositis in different clinical contexts and resource availability. It is inferred that the solutions presented demonstrate promising results in the management of the condition in pediatric cancer patients.

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References

ANDRIAKOPOULOU, C. S. et al. Prevention and Treatment of Oral Mucositis in Pediatric Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials. In Vivo, v. 38, n. 3, p. 1016-1029, 2024.

HAFNER, D. et al. Photobiomodulation for Chemotherapy-Induced Oral Mucositis in Pediatric Patients. Biomolecules, v. 13, n. 3, p. 418, 2023.

HAO, S.; JI, L.; WANG, Y. Effect of Honey on Pediatric Radio/Chemotherapy-Induced Oral Mucositis (R/CIOM): A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine, v. 2022, p. 6906439, 2022

HORVAT ALEKSIJEVIĆ, L. et al. Oral Mucosal Lesions in Childhood. Dentistry Journal, v. 10, n. 11, p. 214, 2022.

NURHIDAYAH, I. et al. The Effect of Oral Care Intervention in Mucositis Management Among Pediatric Cancer Patients: An Updated Systematic Review. Journal of Multidisciplinary Healthcare, v. 17, p. 3497-3511, 2024.

PATEL, P. et al. Clinical practice guideline for the prevention of oral and oropharyngeal mucositis in pediatric cancer and hematopoietic stem cell transplant patients: 2021 update. European Journal of Cancer, v. 154, p. 92-101, 2021.

Published

2026-04-06

How to Cite

DA SILVA, Chiara Ulhiana Cypriani; DE MEDEIROS, Maely Alves; DE SOUZA, Geovanna Maria Ramos Porto; RIBEIRO, Amanda Marques; LOURES FILHO, Eduardo; DOS SANTOS, Maria Láysi Santana; FEITOSA, Pedro Kaique Coelho; OLIVEIRA, Rafael Amaral. PROTOCOLS FOR THE MANAGEMENT OF PEDIATRIC ORAL MUCOSITIS. LUMEN ET VIRTUS, [S. l.], v. 17, n. 59, p. e12781, 2026. DOI: 10.56238/levv17n59-009. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/12781. Acesso em: 8 apr. 2026.