THERAPEUTIC MANAGEMENT OF TAKOTSUBO CARDIOMYOPATHY: BROKEN HEART SYNDROME

Authors

  • Patrícia Natsumi Figueiredo Dohara Author
  • Ryan Rafael Barros de Macedo Author
  • Murilo de Barros Vegini Author
  • Leonardo Macedo Silva Júnior Author
  • Felipe Rezende Rangel Rodrigues Author
  • Brena Bispo de Souza Medeiros Author
  • Alex Canarin Omari Author
  • Morgana Ribeiro da Rocha Author
  • Juliana da Silva Pessoa Author
  • Pedro Vianna Carréri Author
  • Gabriela Decker Author
  • Fernando Malachias de Andrade Bergamo Author

DOI:

https://doi.org/10.56238/levv17n57-012

Keywords:

Takotsubo Cardiomyopathy, Stress-Induced Cardiomyopathy, Acute Heart Failure, Left Ventricular Dysfunction, Clinical Management

Abstract

Takotsubo cardiomyopathy, also known as broken heart syndrome or stress-related cardiomyopathy, is an acute and usually reversible cardiac condition characterized by transient left ventricular dysfunction without significant coronary obstruction. Its clinical presentation can be indistinguishable from acute myocardial infarction, including chest pain, electrocardiographic changes, and elevated cardiac markers. Although initially considered benign, recent evidence demonstrates a significant risk of complications such as arrhythmias, cardiogenic shock, and recurrence, as well as morbidity and mortality rates comparable to those of acute coronary syndrome. Prevalence is higher in postmenopausal women, but cases are also described in other contexts, such as the peripartum period, reinforcing the need for differential diagnosis and appropriate clinical follow-up. This study consisted of a narrative, qualitative, descriptive, and retrospective literature review conducted in the PubMed database between 2021 and 2025, using the descriptors "Takotsubo cardiomyopathy," "Management," and "Diagnosis." Full articles in Portuguese and English were included, excluding duplicates and studies with methodological weaknesses. It is concluded that Takotsubo cardiomyopathy requires an individualized therapeutic approach, early recognition, and multidisciplinary clinical follow-up, considering the risk of recurrence and psychosocial impacts

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References

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Published

2026-02-05

How to Cite

DOHARA, Patrícia Natsumi Figueiredo et al. THERAPEUTIC MANAGEMENT OF TAKOTSUBO CARDIOMYOPATHY: BROKEN HEART SYNDROME. LUMEN ET VIRTUS, [S. l.], v. 17, n. 57, p. e12064, 2026. DOI: 10.56238/levv17n57-012. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/12064. Acesso em: 8 feb. 2026.