COMPARISON BETWEEN IMMEDIATE AND DELAYED LOADING IN THE ALL-ON-4 PROTOCOL FOR ATROPHIC MAXILLAE
DOI:
https://doi.org/10.56238/levv16n55-115Keywords:
All-on-4, Immediate Loading, Delayed Loading, Atrophic Maxilla, Implant DentistryAbstract
Oral rehabilitation of patients with atrophic maxillae represents a clinical challenge in implant dentistry due to the limited bone availability for the placement of conventional implants. Although the All-on-4 protocol is widely used as a predictable and minimally invasive alternative, controversies remain in the literature regarding the ideal timing for prosthetic loading. This study aimed to analyze and compare scientific evidence published over the past ten years on the effectiveness of immediate and delayed loading protocols applied to the All-on-4 concept in atrophic maxillae. This is a narrative literature review conducted between September and November 2025 in the PubMed, SciELO, SpringerLink, MDPI, and Research, Society and Development Journal databases, using descriptors defined by MeSH and DeCS in both Portuguese and English. Original articles, systematic reviews, and clinical reports published between 2015 and 2025 comparing both loading protocols were included. Data were analyzed descriptively and comparatively, focusing on implant survival rates, marginal bone loss, and patient satisfaction. The results showed high implant survival rates (93.8%–99.3%) and mean marginal bone loss ranging from 0.8 to 1.5 mm, with high patient satisfaction in both protocols. It was concluded that both immediate and delayed loading are safe and effective approaches, and the choice of protocol should be individualized according to the patient’s clinical conditions. The findings contribute to improving treatment planning and evidence-based clinical practice in implant dentistry.
Downloads
References
ABDUNABI, M.; OSMAN, R. B.; ABUZAYED, B. Comparison between immediate and delayed loading protocols for full-arch implant-supported prostheses: a clinical evaluation. Journal of Prosthodontic Research, v. 63, n. 2, p. 237–244, 2019.
ALBREKTSSON, T.; ZARB, G. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. The International Journal of Oral & Maxillofacial Implants, v. 1, n. 1, p. 11–25, 1986.
ARAÚJO, L. C. Avaliação clínica da reabilitação de maxilas atróficas pelo protocolo All-on-4 com carga imediata: estudo longitudinal de cinco anos. Brazilian Dental Science, v. 28, n. 1, p. 1–9, 2025.
ATIEH, M. A.; ALSAADI, G.; FEGAN, D.; PAYNE, A. G. T. Immediate loading with the All-on-4 concept: a systematic review and meta-analysis. Clinical Implant Dentistry and Related Research, v. 19, n. 5, p. 1043–1055, 2017.
EL-DIN GOMAA, M.; OSAMA, H. Marginal bone loss around immediately and delayed loaded implants in edentulous maxilla using the All-on-4 concept: a controlled clinical study. Egyptian Dental Journal, v. 65, n. 4, p. 3129–3140, 2019.
MENDES, K. D. S.; SILVEIRA, R. C. C. P.; GALVÃO, C. M. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto – Enfermagem, v. 17, n. 4, p. 758–764, 2008.
NAJAFI, E.; PEÑARANDA, M.; MONJE, A. Clinical outcomes of immediate versus delayed loading in full-arch implant rehabilitations with the All-on-4 concept: a prospective study. The International Journal of Oral and Maxillofacial Surgery, v. 45, n. 8, p. 1020–1028, 2016.
PATEL, H.; KALRA, N.; THAKUR, P. Immediate vs delayed loading of implants in atrophic maxilla using All-on-4: a systematic review and meta-analysis. Journal of Prosthodontic Research, v. 67, n. 3, p. 221–234, 2023.
PEITSINIS, E.; KOURTIS, S.; KOTSOUGIANNI, Z. Evaluation of the All-on-4 concept with immediate versus delayed loading in atrophic maxilla: a long-term clinical follow-up study. Clinical Oral Implants Research, v. 36, n. 2, p. 215–224, 2025.
RAINERI, A. R. Reabilitação total fixa em maxilas atróficas com o protocolo All-on-4: análise clínica e satisfação do paciente. Research, Society and Development Journal (RSD), v. 13, n. 2, p. e425132248, 2024.
ROSA, M. F.; MARTINS, P. C.; SANTOS, J. C. Immediate loading in the All-on-4 concept: evaluation of bone loss and patient satisfaction in the first year of follow-up. Revista Odonto Ciência, v. 33, n. 3, p. 189–197, 2018.
ROTHER, E. T. Revisão narrativa: etapa inicial do processo de pesquisa científica. Revista Acta Paulista de Enfermagem, v. 20, n. 2, p. v–vi, 2007.
SOTO-PENALOZA, D.; PEÑARANDA, M.; CORDERO, R. All-on-4 immediate loading concept for the rehabilitation of atrophic maxilla: a 3-year prospective clinical study. Journal of Prosthodontic Research, v. 61, n. 4, p. 387–393, 2017.
SRISUTHEP, P.; KLOMSOM, C.; PISITKUL, S. Comparison of immediate and delayed loading protocols in the All-on-4 concept: a systematic review. Clinical Implant Dentistry and Related Research, v. 21, n. 6, p. 1184–1193, 2019.
UESUGI, S.; MALO, P.; LOPES, A. Long-term outcomes of the All-on-4 treatment concept in severely atrophic maxillae: a 17-year retrospective cohort study. Clinical Oral Implants Research, v. 34, n. 1, p. 45–57, 2023.