HEMOPHAGOCYTIC SYNDROME SECONDARY TO ANTICONVULSANT-RELATED DRESS SYNDROME: A CASE REPORT
DOI:
https://doi.org/10.56238/levv16n55-069Keywords:
Hemophagocytic Syndrome, DRESS Syndrome, EosinophiliaAbstract
DRESS (Drug Reaction with Eosinophilia and Systemic Inflammation) is a serious adverse reaction that can present with significant multivisceral involvement. The exacerbated immune activation that occurs in DRESS syndrome can trigger hemophagocytic syndrome, generating intense systemic inflammation with unfavorable and potentially fatal clinical evolution. The association between hemophagocytic syndrome and DRESS is rare; however, early recognition of signs and symptoms is fundamental for timely diagnosis and treatment, reducing the likelihood of adverse outcomes and increasing the chances of therapeutic success.
Downloads
References
1.Manual do residente de Clínica Médica 3° edição – Seção 21: Alergia e Imunologia, capitulo 213: Reações Adversas a drogas
2. Síndrome Hemofagocítica – Uma abordagem para o tratamento. Revista Indiana de Medicina de Cuidados Críticos. 2019 Set;23(Supl 3):S191–S196. doi: 10.5005/jp-journals-10071-23251
3. UpToDate. Disponível em: https://www.uptodate.com/contents/treatment-and-prognosis-of-hemophagocytic lymphohistiocytosis?search=sindrome%20hemofagocitica&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2
4. UpToDate. Disponível em: https://www.uptodate.com/contents/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress?search=sindrome%20dress&source=search_result&selectedTitle=1~127&usage_type=default&display_rank=1
5.UpToDate. Disponível em: https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-hemophagocytic-lymphohistiocytosis?search=sindrome%20hemofagocitica&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1