HEMOPHAGOCYTIC SYNDROME SECONDARY TO ANTICONVULSANT-RELATED DRESS SYNDROME: A CASE REPORT

Authors

  • Caroline Cristina de Melo Author
  • Bianca Vieira Albanese Author
  • Lucas Ferreira Borges Author
  • Ana Luara Barcelos Silva Author
  • Francesco Carlo Maronese Author
  • Marcos Donisete Granado Júnior Author

DOI:

https://doi.org/10.56238/levv16n55-069

Keywords:

Hemophagocytic Syndrome, DRESS Syndrome, Eosinophilia

Abstract

DRESS (Drug Reaction with Eosinophilia and Systemic Inflammation) is a serious adverse reaction that can present with significant multivisceral involvement. The exacerbated immune activation that occurs in DRESS syndrome can trigger hemophagocytic syndrome, generating intense systemic inflammation with unfavorable and potentially fatal clinical evolution. The association between hemophagocytic syndrome and DRESS is rare; however, early recognition of signs and symptoms is fundamental for timely diagnosis and treatment, reducing the likelihood of adverse outcomes and increasing the chances of therapeutic success.

Downloads

Download data is not yet available.

References

1.Manual do residente de Clínica Médica 3° edição – Seção 21: Alergia e Imunologia, capitulo 213: Reações Adversas a drogas

2. Síndrome Hemofagocítica – Uma abordagem para o tratamento. Revista Indiana de Medicina de Cuidados Críticos. 2019 Set;23(Supl 3):S191–S196. doi: 10.5005/jp-journals-10071-23251

3. UpToDate. Disponível em: https://www.uptodate.com/contents/treatment-and-prognosis-of-hemophagocytic lymphohistiocytosis?search=sindrome%20hemofagocitica&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2

4. UpToDate. Disponível em: https://www.uptodate.com/contents/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress?search=sindrome%20dress&source=search_result&selectedTitle=1~127&usage_type=default&display_rank=1

5.UpToDate. Disponível em: https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-hemophagocytic-lymphohistiocytosis?search=sindrome%20hemofagocitica&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1

Published

2025-12-12

How to Cite

DE MELO, Caroline Cristina; ALBANESE, Bianca Vieira; BORGES, Lucas Ferreira; SILVA, Ana Luara Barcelos; MARONESE, Francesco Carlo; GRANADO JÚNIOR, Marcos Donisete. HEMOPHAGOCYTIC SYNDROME SECONDARY TO ANTICONVULSANT-RELATED DRESS SYNDROME: A CASE REPORT. LUMEN ET VIRTUS, [S. l.], v. 16, n. 55, p. e11034, 2025. DOI: 10.56238/levv16n55-069. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/11034. Acesso em: 17 feb. 2026.