THE RELATIONSHIP OF TOXOPLASMA GONDII WITH NEUROCHEMISTRY IN PSYCHOPATHOLOGIES WITH EMPHASIS ON SCHIZOPHRENIA: BIBLIOGRAPHIC REVIEW

Authors

  • Antônio José Ferreira Maia Russo Author
  • Felipe Gouvea de Souza Author
  • Murilo Tavares Amorim Author
  • Tinara Leila de Souza Aarão Author
  • Célio Amoedo de Melo Author
  • Cláudia Simone Baltazar de Oliveira Author
  • Patrícia Bentes Marques Author

DOI:

https://doi.org/10.56238/levv16n54-16

Keywords:

Toxoplasma, Psychopathologies, Depression, Schizophrenia

Abstract

Toxoplasma gondii (T. gondii) is an obligate intracellular parasite. It is estimated that one-third of the world's population is affected, making it one of the most prevalent human parasites. Studies indicate a possible correlation between Toxoplasma gondii and psychopathologies such as schizophrenia, anxiety, depression and bipolar disorder, indicating dopaminergic and morphological alterations, thus causing changes in the behavior of those infected. This work aims to describe from a bibliographic review, the possible connection between Toxoplasma gondii with cases of psychopathologies. An integrative bibliographic search was carried out in the following databases: Pubmed, Lilacs, Scholar Google, Medline and Scielo. The articles went through an evaluation to be included or discarded; these were evaluated by inclusion and exclusion criteria. The requirement was to have been produced between 2010 and 2025 exclused studies published in the Portuguese language. A survey of clinical cases addressed in scientific papers was carried out seeking symptomatology, reasons that led to the possible correlation of toxoplasmosis and psychological disorders. According to the results obtained, it is noted that the multifactorial occasion of psychopathologies becomes inconclusive about the real correlation between Toxoplasma Gondii and psychopathologies, since there are no neurochemical methods and also variables such as socioeconomic, geographic, epidemiological, genetic factors, age, lifestyle and gender do not corroborate to attest this link, although there is evidence that makes this connection possible.

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Published

2025-11-27

How to Cite

RUSSO, Antônio José Ferreira Maia; DE SOUZA, Felipe Gouvea; AMORIM, Murilo Tavares; AARÃO, Tinara Leila de Souza; DE MELO, Célio Amoedo; DE OLIVEIRA, Cláudia Simone Baltazar; MARQUES, Patrícia Bentes. THE RELATIONSHIP OF TOXOPLASMA GONDII WITH NEUROCHEMISTRY IN PSYCHOPATHOLOGIES WITH EMPHASIS ON SCHIZOPHRENIA: BIBLIOGRAPHIC REVIEW. LUMEN ET VIRTUS, [S. l.], v. 16, n. 54, p. e10490, 2025. DOI: 10.56238/levv16n54-16. Disponível em: https://periodicos.newsciencepubl.com/LEV/article/view/10490. Acesso em: 13 feb. 2026.