MAIN CLINICAL MANIFESTATIONS OF SCHIZOPHRENIA AND POSSIBLE APPROACHES: A SYSTEMATIC REVIEW

Abstract

Objective: The purpose of this analysis was to present current knowledge about the main signs, symptoms, and associated conditions that impact people with schizophrenia. Methodology: The investigations were carried out through searches in the PubMed Central (PMC) and Virtual Health Library (VHL) data platforms. Three search terms were used in conjunction with the Boolean operator "AND": Schizophrenia, Signs and Symptoms, Clinical Diagnosis. From this research, 490 works were found, later evaluated according to the selection criteria. Of these, 419 studies came from the PubMed database and 71 from the Virtual Health Library. After applying the inclusion and exclusion criteria, 24 articles from PubMed and 1 from the Virtual Health Library were selected, totaling 25 studies to compose the analysis. Results: The investigations highlight the connection between psychotic disorders, such as schizophrenia and depression, evidencing the relevance of continuity in research and interdisciplinary interaction to improve the recognition and treatment of these conditions. The discovery of biological markers and a more detailed analysis of clinical characteristics are essential to develop more effective treatments, with the aim of providing a better quality of life for patients. Conclusion: The combination of collaborative strategies between different medical areas and the use of advanced technologies, such as artificial intelligence and machine learning, open up new possibilities for early recognition and customized treatments of schizophrenia. In short, the evolution in the care of these intricate conditions requires an integrated and multidisciplinary approach, aimed at meeting the specific demands of patients and ensuring their overall well-being.