CONGENITAL DENGUE AND NEONATAL NEUROLOGICAL MANIFESTATIONS: A SCOPING REVIEW

Authors

  • Ricardo Marafigo Zander Author
  • Ianka do Amaral Caetano Author
  • Aline Domingues Stumpf Mendoza Author
  • Laiza Moura Cunha Costa Luz Author
  • Jessyca Twany Demogalski Author
  • Cristina Berger Fadel Author
  • Leonardo Welling Author
  • Fabiana Bucholdz Teixeira Alves Author

DOI:

https://doi.org/10.56238/ERR01v10n5-046

Keywords:

Dengue, Vertical Transmission of Infectious Disease, Neurologic Manifestations, Neonate

Abstract

Rationale: Despite the rising number of dengue cases in pregnant women and the possibility of vertical transmission with neonatal neurological repercussions, the effects of congenital DENV infection remain poorly understood and scarcely documented in the scientific literature.

Objective: To map the neurological manifestations resulting from congenital dengue virus infection in neonates and to identify and explore scientific gaps related to improving maternal and child healthcare in the context of this condition.

Methods: This scoping review was conducted based on a search strategy guided by the research question: “What are the neonatal neurological manifestations resulting from congenital dengue?”, with clear definition of the study population, concept, and context. The databases Embase, LILACS, PubMed, Scopus, Web of Science, and gray literature sources were searched up to June 2024.

Results: A total of 178 articles were identified. After applying methodological filters and inclusion criteria, five studies were selected. Bibliographic data, aspects related to congenital dengue, and study conclusions were presented.

Conclusion: The scoping review identified evidence of neonatal neurological manifestations associated with congenital DENV infection, highlighting its impact on fetal health and the need for clinical and neurological surveillance of exposed neonates.

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Published

2025-10-29

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How to Cite

CONGENITAL DENGUE AND NEONATAL NEUROLOGICAL MANIFESTATIONS: A SCOPING REVIEW. (2025). ERR01, 10(5), e9364. https://doi.org/10.56238/ERR01v10n5-046