USO DE FIBRINA RICA EM PLAQUETAS EM LEVANTAMENTO DE SEIOS MAXILARES
DOI:
https://doi.org/10.56238/arev7n10-199Palavras-chave:
Levantamento de Seio Maxilar, Fibrina Rica em Plaquetas, Regeneração Óssea, ImplantodontiaResumo
A reabilitação com implantes na maxila posterior atrófica frequentemente requer procedimentos de aumento do seio maxilar. A Fibrina Rica em Plaquetas (PRF), um concentrado plaquetário autólogo, consolidou-se como um biomaterial de grande interesse para otimizar o processo regenerativo. O objetivo deste trabalho foi realizar uma revisão de literatura, a partir de 19 artigos selecionados, para analisar a eficácia clínica, as indicações e os debates atuais sobre o uso da PRF em cirurgias de levantamento do assoalho do seio maxilar. A análise da literatura demonstra que a PRF, quando utilizada como material de enxerto único, é uma alternativa previsível e custo-efetiva, suportada por estudos de longo prazo que mostram estabilidade volumétrica e altas taxas de sucesso dos implantes. Contudo, seu benefício como aditivo a outros biomateriais permanece controverso; as evidências não suportam um aumento significativo no volume ósseo final, embora sugiram uma aceleração da maturação óssea inicial. Conclui-se que a PRF é uma ferramenta versátil e consolidada, com forte evidência para seu uso como enxerto autônomo e no manejo de complicações. Sua aplicação como aditivo, no entanto, deve ser indicada para otimizar a biologia do processo cicatricial, e não primariamente como um meio para se obter maior volume ósseo.
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Referências
ALMUTAIRI, M. et al. Leukocyte-Platelet-Rich Fibrin Combined With Demineralized Bovine Bone Mineral for Maxillary Sinus Augmentation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Cureus, v. 17, n. 6, p. e85306, 2025. DOI: https://doi.org/10.7759/cureus.85306
ALVES, M. A. L. et al. Long-Term Success of Dental Implants in Atrophic Maxillae: A 3-Year Case Series Using Hydroxyapatite and L-PRF. Bioengineering, v. 11, n. 12, p. 1207, 2024. DOI: https://doi.org/10.3390/bioengineering11121207
AWAD, Z. I.; BEIT, Z. Z. K. The use of platelet-rich fibrin prepared with titanium tubes (T-PRF) in external maxillary sinus lift combined with simultaneous implant placement (case series). International Journal of Surgery Case Reports, v. 136, p. 111994, 2025. DOI: https://doi.org/10.1016/j.ijscr.2025.111994
CHOUDHARY, S. et al. Outcomes Following Hydraulic Pressure Indirect Sinus Lift in Cases of Simultaneous Implant Placement With Platelet-Rich Fibrin. Cureus, v. 14, n. 8, p. e28087, 2022. DOI: https://doi.org/10.7759/cureus.28087
DAMSAZ, M. et al. Evidence-Based Clinical Efficacy of Leukocyte and Platelet-Rich Fibrin in Maxillary Sinus Floor Lift, Graft and Surgical Augmentation Procedures. Frontiers in Surgery, v. 7, p. 537138, 2020. DOI: https://doi.org/10.3389/fsurg.2020.537138
FRANCISCO, L. et al. Sinus Floor Augmentation with Synthetic Hydroxyapatite (NanoBone®) in Combination with Platelet-Rich Fibrin: A Case Series. Biomedicines, v. 12, n. 8, p. 1661, 2024. DOI: https://doi.org/10.3390/biomedicines12081661
GASPARRO, R. et al. Effectiveness of Autologous Platelet Concentrates in the Sinus Lift Surgery: Findings from Systematic Reviews and Meta-Analyses. Dentistry Journal, v. 12, n. 4, p. 101, 2024. DOI: https://doi.org/10.3390/dj12040101
HUANG, L.-R. et al. Hydraulic sinus floor elevation using advanced platelet-rich fibrin: A randomized clinical trial with two-dimensional radiographic results. Journal of Prosthodontic Research, v. 69, n. 2, p. 275-284, 2025. DOI: https://doi.org/10.2186/jpr.JPR_D_24_00065
IDIRI, K. et al. The Effectiveness of the Addition of Platelet-Rich Fibrin to Bovine Xenografts in Sinus and Bone Ridge Augmentation: A Systematic Review. Journal of Functional Biomaterials, v. 14, n. 7, p. 389, 2023. DOI: https://doi.org/10.3390/jfb14070389
LV, H. et al. Flapless osteotome-mediated sinus floor elevation using platelet-rich fibrin versus lateral approach using deproteinised bovine bone mineral for residual bone height of 2-6 mm: A randomised trial. Clinical Oral Implants Research, v. 33, n. 7, p. 700-712, 2022. DOI: https://doi.org/10.1111/clr.13934
MALCANGI, G. et al. Maxillary Sinus Augmentation Using Autologous Platelet Concentrates (Platelet-Rich Plasma, Platelet-Rich Fibrin, and Concentrated Growth Factor) Combined with Bone Graft: A Systematic Review. Cells, v. 12, n. 13, p. 1797, 2023. DOI: https://doi.org/10.3390/cells12131797
MITREA, M. et al. THE SINUS LIFT PROCEDURE APPLIED IN CASES WHERE THE THICKNESS OF THE ALVEOLAR BONE IS INSUFFICIENT USING DOUBLE PRF AS WELL AS IN THE CASE OF AN INTRASINUS MUCOCELE. Romanian Journal of Oral Rehabilitation, v. 15, n. 1, p. 66-81, 2023.
ORTEGA-MEJIA, H. et al. Platelet-Rich Plasma in Maxillary Sinus Augmentation: Systematic Review. Materials, v. 13, n. 3, p. 622, 2020. DOI: https://doi.org/10.3390/ma13030622
OTERO, A. I. P. et al. Sinus Lift Associated with Leucocyte-Platelet-Rich Fibrin (Second Generation) for Bone Gain: A Systematic Review. Journal of Clinical Medicine, v. 11, n. 7, p. 1888, 2022. DOI: https://doi.org/10.3390/jcm11071888
POWELL, C. A. et al. The application of leukocyte- and platelet-rich fibrin (L-PRF) in maxillary sinus augmentation. Clinical Advances in Periodontics, v. 12, n. 4, p. 277-286, 2022. DOI: https://doi.org/10.1002/cap.10216
QIU, P. et al. Assessment of the efficacy of autologous blood preparations in maxillary sinus floor elevation surgery: a systematic review and meta-analysis. BMC Oral Health, v. 24, n. 1, p. 1171, 2024. DOI: https://doi.org/10.1186/s12903-024-04938-8
REIS, G. G. D. et al. Sinus Floor Elevation With Platelet-Rich Fibrin From Horizontal Centrifugation and Xenograft: Randomized Clinical Trial. Clinical Implant Dentistry and Related Research, v. 27, p. e70093, 2025. DOI: https://doi.org/10.1111/cid.70093
SALGADO-PERALVO, A.-O. et al. Treatment of sinus membrane perforations during sinus lift surgeries using leukocyte and platelet-rich fibrin: A report of three cases. Journal of Clinical and Translational Research, v. 8, n. 5, p. 360-368, 2022.
VALENTINI, P. et al. APCs in sinus floor augmentation. Periodontology 2000, v. 97, n. 1, p. 254-270, 2025. DOI: https://doi.org/10.1111/prd.12554
YU, S. et al. Early tissue and healing responses after maxillary sinus augmentation using horizontal platelet rich fibrin bone blocks. BMC Oral Health, v. 23, n. 1, p. 589, 2023. DOI: https://doi.org/10.1186/s12903-023-03228-z
