ESCLEROSE PERITONEAL ENCAPSULANTE ASSOCIADA À PRESENÇA DE CORPOS ESTRANHOS: UMA REVISÃO SISTEMÁTICA
DOI:
https://doi.org/10.56238/arev7n12-110Palavras-chave:
Esclerose Peritoneal Encapsulante, Corpo Estranho, Fibrose Peritoneal, Cirurgia Digestiva, EnteróliseResumo
A esclerose peritoneal encapsulante (EPE) é uma condição rara e potencialmente fatal caracterizada pela formação progressiva de uma cápsula fibrosa envolvendo as alças intestinais, resultando em obstrução e comprometimento funcional grave. Este estudo tem como objetivo revisar sistematicamente a literatura sobre a EPE associada à presença de corpos estranhos, com ênfase na fisiopatologia, diagnóstico e abordagem cirúrgica. Foram incluídos 41 estudos entre 1907 e 2025, abrangendo relatos de caso, séries clínicas e revisões observacionais. Os resultados demonstraram forte correlação entre a presença de materiais sintéticos, como fios de sutura não absorvíveis, drenos e fragmentos de cateteres e o desenvolvimento de processo inflamatório crônico com fibrose peritoneal subsequente. A enterólise ampla, associada à remoção completa do corpo estranho, configurou o tratamento de escolha, com significativa redução da mortalidade quando realizada precocemente. Conclui-se que a EPE relacionada a corpos estranhos é uma entidade cirúrgica complexa que requer diagnóstico precoce, intervenção completa e acompanhamento multidisciplinar para otimizar os desfechos clínicos e prevenir recidivas.
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Referências
Abrahams AC, Habib SM, Dendooven A, Riser BL, van der Veer JW, Toorop RJ, et al. Patients with encapsulating peritoneal sclerosis have increased peritoneal expression of connective tissue growth factor, transforming growth factor-β1, and vascular endothelial growth factor. PLoS One. 2014;9(11):e112050. DOI: https://doi.org/10.1371/journal.pone.0112050
Akbulut S. Accurate definition and management of idiopathic sclerosing encapsulating peritonitis. World J Gastroenterol. 2015;21(2):675-687. DOI: https://doi.org/10.3748/wjg.v21.i2.675
Alston H, Fan S, Nakayama M. Encapsulating peritoneal sclerosis. Semin Nephrol. 2017;37(1):93-102. DOI: https://doi.org/10.1016/j.semnephrol.2016.10.010
Andrion A, Pira E, Mollo F. Peritoneal plaques and asbestos exposure. Arch Pathol Lab Med. 1983;107(11):609-610.
Árnadóttir M, Jónasson JG, Indridason ÓS. Encapsulating peritoneal sclerosis following a peritoneal foreign body reaction to Dacron fibres: a case report. NDT Plus. 2011;4:107-109. DOI: https://doi.org/10.1093/ndtplus/sfq202
Aroeira LS, Aguilera A, Sánchez-Tomero JA, Bajo MA, del Peso G, Jiménez-Heffernan JA, et al. Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions. J Am Soc Nephrol. 2007;18(7):2004-2013. DOI: https://doi.org/10.1681/ASN.2006111292
Betjes MG, Habib SM, Boeschoten EW, Hemke AC, Struijk DG, Westerhuis R, et al. Significant decreasing incidence of encapsulating peritoneal sclerosis in the Dutch population of peritoneal dialysis patients. Perit Dial Int. 2017;37(3):230-234. DOI: https://doi.org/10.3747/pdi.2016.00109
Braun N, Alscher DM, Fritz P, Edenhofer I, Kimmel M, Gaspert A, et al. Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis. Nephrol Dial Transplant. 2011;26(3):1033-1041. DOI: https://doi.org/10.1093/ndt/gfq488
Brown EA, Bargman J, van Biesen W, Chang MY, Finkelstein FO, Hurst H, et al. Length of time on peritoneal dialysis and encapsulating peritoneal sclerosis: position paper for ISPD update 2017. Perit Dial Int. 2017;37(4):362-374. DOI: https://doi.org/10.3747/pdi.2017.00018
Casas JD, Mariscal A, Martínez N. Peritoneal encapsulation: CT appearance. AJR Am J Roentgenol. 1998;171(4):1017-1019. DOI: https://doi.org/10.2214/ajr.171.4.9762988
Danford CJ, Lin SC, Smith MP, Wolf JL. Encapsulating peritoneal sclerosis. World J Gastroenterol. 2018;24(28):3101-3111. DOI: https://doi.org/10.3748/wjg.v24.i28.3101
Eltringham WK, Espiner HJ, Windsor CW, Griffiths DA, Davies JD, Baddeley H, et al. Sclerosing peritonitis due to practolol: a report on 9 cases and their surgical management. Br J Surg. 1977;64(4):229-235. DOI: https://doi.org/10.1002/bjs.1800640402
Frigerio L, Taccagni GL, Mariani A, Mangili G, Ferrari A. Idiopathic sclerosing peritonitis associated with florid mesothelial hyperplasia, ovarian fibromatosis, and endometriosis. Am J Obstet Gynecol. 1997;176(3):721-722. DOI: https://doi.org/10.1016/S0002-9378(97)70581-7
Gandhi VC, Humayun HM, Ing TS, Daugirdas JT, Jablokow VR, Iwatsuki S, et al. Sclerotic thickening of the peritoneal membrane in maintenance peritoneal dialysis patients. Arch Intern Med. 1980;140(9):1201-1203. DOI: https://doi.org/10.1001/archinte.1980.00330200077024
Garosi G, Di Paolo N. Morphological aspects of peritoneal sclerosis. J Nephrol. 2001;14(Suppl 4):S30-S38.
Garosi G, Di Paolo N. Morphological aspects of peritoneal sclerosis. J Nephrol. 2001;14(Suppl 4):S30-S38.
Gupta S, Woodrow G. Successful treatment of fulminant encapsulating peritoneal sclerosis following fungal peritonitis with tamoxifen. Clin Nephrol. 2007;68(2):125-129. DOI: https://doi.org/10.5414/CNP68125
Habib SM, Betjes MGH, Fieren MWJA, Boeschoten EW, Abrahams AC, Boer WH, et al. Management of encapsulating peritoneal sclerosis: a guideline on optimal and uniform treatment. Neth J Med. 2011;69(11):500-507.
Habib SM, Betjes MGH, Fieren MWJA, Boeschoten EW, Abrahams AC, Boer WH, et al. Management of encapsulating peritoneal sclerosis: a guideline on optimal and uniform treatment. Neth J Med. 2011;69(11):500-507.
Hoshii S, Honda M, Itami N, Oh S, Matsumura C, Moriya S, et al. Sclerosing encapsulating peritonitis in pediatric peritoneal dialysis patients. Pediatr Nephrol. 2000;14(3):275-279. DOI: https://doi.org/10.1007/s004670050758
Jagirdar RM, Bozikas A, Zarogiannis SG, Bartosova M, Schmitt CP, Liakopoulos V. Encapsulating peritoneal sclerosis: pathophysiology and current treatment options. Int J Mol Sci. 2019;20(22):5765. DOI: https://doi.org/10.3390/ijms20225765
Johnson DW, Cho Y, Livingston BE, Hawley CM, McDonald SP, Brown FG, et al. Encapsulating peritoneal sclerosis: incidence, predictors, and outcomes. Kidney Int. 2010;77(10):904-911. DOI: https://doi.org/10.1038/ki.2010.16
Kaman L, Iqbal J, Thenozhi S. Sclerosing encapsulating peritonitis: complication of laparoscopic cholecystectomy. J Laparoendosc Adv Surg Tech A. 2010;20(3):253-255. DOI: https://doi.org/10.1089/lap.2010.0024
Kaur S, Doley RP, Chabbhra M, Kapoor R, Wig J. Post trauma abdominal cocoon. Int J Surg Case Rep. 2015;7C:64-65. DOI: https://doi.org/10.1016/j.ijscr.2014.10.081
Kawaguchi Y, Kawanishi H, Fukui H, Hara S, Imada A, Kubo H, et al. Encapsulating peritoneal sclerosis in Japan: a prospective, controlled, multicenter study. Am J Kidney Dis. 2004;44(4):729-737.
Kawaguchi Y, Kawanishi H, Fukui H, Hara S, Imada A, Kubo H, et al. Encapsulating peritoneal sclerosis in Japan: a prospective, controlled, multicenter study. Am J Kidney Dis. 2004;44(4):729-737. DOI: https://doi.org/10.1016/S0272-6386(04)00953-9
Kawaguchi Y, Kawanishi H, Mujais S, Topley N, Oreopoulos DG. Encapsulating peritoneal sclerosis: definition, etiology, diagnosis, and treatment. Perit Dial Int. 2000;20(Suppl 4):S43-S55.
Kawanishi H, Kawaguchi Y, Mujais S, Topley N, Oreopoulos DG. Encapsulating peritoneal sclerosis: definition, etiology, diagnosis, and treatment. Perit Dial Int. 2000;20(Suppl 4):S43-S55. DOI: https://doi.org/10.1177/089686080002004S04
Kawanishi H, Moriishi M. Epidemiology of encapsulating peritoneal sclerosis in Japan. Perit Dial Int. 2005;25(Suppl 4):S14-S18. DOI: https://doi.org/10.1177/089686080502504S03
Lambie MR, Chess J, Summers AM, Williams PF, Topley N, Davies SJ. Peritoneal inflammation precedes encapsulating peritoneal sclerosis: results from the GLOBAL Fluid Study. Nephrol Dial Transplant. 2016;31(3):480-486. DOI: https://doi.org/10.1093/ndt/gfv440
Li N, Zhu W, Li Y, Gong J, Gu L, Li M, et al. Surgical treatment and perioperative management of idiopathic abdominal cocoon: single-center review of 65 cases. World J Surg. 2014;38(8):1860-1867. DOI: https://doi.org/10.1007/s00268-014-2458-6
López-Antón M, Lambie M, López-Cabrera M, Schmitt CP, Ruiz-Carpio V, Bartosova M, et al. miR-21 promotes fibrogenesis in peritoneal dialysis. Am J Pathol. 2017;187(7):1537-1550. DOI: https://doi.org/10.1016/j.ajpath.2017.03.007
Moinuddin Z, Summers A, van Dellen D, Augustine T, Herrick SE. Encapsulating peritoneal sclerosis—a rare but devastating peritoneal disease. Front Physiol. 2015;5:470. DOI: https://doi.org/10.3389/fphys.2014.00470
Moriles KE, Hashmi MF. Encapsulating peritoneal sclerosis. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
Morrow EH, Gallo AE, Melcher ML. Sclerosing peritonitis after kidney transplantation: a not-so-silky cocoon. Dig Dis Sci. 2011;56(2):307-310. DOI: https://doi.org/10.1007/s10620-010-1471-3
Nakayama M, Miyazaki M, Honda K, Kasai K, Tomo T, Nakamoto H, et al. Encapsulating peritoneal sclerosis in the era of a multi-disciplinary approach based on biocompatible solutions: the NEXT-PD study. Perit Dial Int. 2014;34(7):766-774. DOI: https://doi.org/10.3747/pdi.2013.00074
Owtschinnikow PJ. Peritonitis chronica fibrosa incapsulata. Arch Klin Chir. 1907;83:623-634.
Rigby RJ, Hawley CM. Sclerosing peritonitis: the experience in Australia. Nephrol Dial Transplant. 1998;13(1):154-159. DOI: https://doi.org/10.1093/ndt/13.1.154
Rottembourg J, Gahl GM, Poignet JL, Mertani E, Strippoli P, Langlois P, et al. Severe abdominal complications in patients undergoing continuous ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc. 1983;20:236-242.
Schaefer B, Bartosova M, Macher-Goeppinger S, Sallay P, Vörös P, Ranchin B, et al. Neutral pH and low–glucose degradation product dialysis fluids induce major early alterations of the peritoneal membrane in children on peritoneal dialysis. Kidney Int. 2018;94(3):419-429. DOI: https://doi.org/10.1016/j.kint.2018.02.022
Takebayashi K, Sonoda H, Shimizu T, Ohta H, Ishida M, Mekata E, et al. Successful surgical approach for a patient with encapsulating peritoneal sclerosis after hyperthermic intraperitoneal chemotherapy: a case report and literature review. BMC Surg. 2014;14:57. DOI: https://doi.org/10.1186/1471-2482-14-57
